The individual relationship between atrial fibrillation sources from CARTOFINDER mapping and atrial cardiomyopathy: The catch me if you can trial.

Background: Targeting individual sources identified during atrial fibrillation (AF) has been used as an ablation strategy with varying results. Objective: Aim of this study was to evaluate the relationship between regions of interest (ROIs) from CARTOFINDER (CF) mapping and atrial cardiomyopathy fro...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 46; no. 12; pp. 1553 - 1565
Autores principales: Guckel, Denise, Piran, Misagh, Bergau, Leonard, Hamriti, Mustapha El, Fink, Thomas, Sciacca, Vanessa, Reil, Jan‐Christian, Braun, Martin, Khalaph, Moneeb, Imnadze, Guram, Kramer, Katharina, Friedrich, Sarah, Rühl, Jasmin, Körperich, Hermann, Sommer, Philipp, Sohns, Christian
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell Dec2023
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
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        10.1111/pace.14847
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        atl: The individual relationship between atrial fibrillation sources from CARTOFINDER mapping and atrial cardiomyopathy: The catch me if you can trial.
      aug:
        au:
          Guckel, Denise
          Piran, Misagh
          Bergau, Leonard
          Hamriti, Mustapha El
          Fink, Thomas
          Sciacca, Vanessa
          Reil, Jan‐Christian
          Braun, Martin
          Khalaph, Moneeb
          Imnadze, Guram
          Kramer, Katharina
          Friedrich, Sarah
          Rühl, Jasmin
          Körperich, Hermann
          Sommer, Philipp
          Sohns, Christian
        affil: Clinic for Electrophysiology, Herz‐ und Diabeteszentrum NRW, Ruhr‐Universität Bochum, Bad Oeynhausen, Germany
      sug:
        subj:
          Atrial Fibrillation Diagnosis
          Heart Atrium Physiopathology
          Myocardial Diseases Diagnosis
          Magnetic Resonance Imaging
          Body Surface Potential Mapping Methods
          Image Enhancement
          Human
          Descriptive Statistics
          Catheter Ablation
          Funding Source
          Contrast Media Diagnostic Use
      ab: Background: Targeting individual sources identified during atrial fibrillation (AF) has been used as an ablation strategy with varying results. Objective: Aim of this study was to evaluate the relationship between regions of interest (ROIs) from CARTOFINDER (CF) mapping and atrial cardiomyopathy from late gadolinium enhancement (LGE) cardiovascular magnetic resonance imaging (CMR). Methods: Twenty consecutive patients underwent index catheter ablation for persistent AF (PERS AF). Pre‐processed LGE CMR images were merged with the results from CF mapping to visualize harboring regions for focal and rotational activities. Atrial cardiomyopathy was classified based on the four Utah stages. Results: Procedural success was achieved in all patients (n = 20, 100%). LGE CMR revealed an intermediate amount of 21.41% ± 6.32% for LA fibrosis. ROIs were identified in all patients (mean no ROIs per patient n = 416.45 ± 204.57). A tendency towards a positive correlation between the total amount of atrial cardiomyopathy and the total number of ROIs per patient (regression coefficient, β = 10.86, p =.15) was observed. The degree of fibrosis and the presence of ROIs per segment showed no consistent spatial correlation (posterior: β = 0.36, p‐value (p) =.24; anterior: β = −0.08, p =.54; lateral: β = 0.31, p = 39; septal: β = −0.12; p =.66; right PVs: β = 0.34, p =.27; left PVs: β = 0.07, p =.79; LAA: β = −0.91, p =.12). 12 months AF‐free survival was 70% (n = 14) after ablation. Conclusion: The presence of ROIs from CF mapping was not directly associated with the extent and location of fibrosis. Further studies evaluating the relationship between focal and rotational activity and atrial cardiomyopathy are mandatory.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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