Functional Magnetic Resonance Imaging Activation During Unscripted Discourse in People With Poststroke Aphasia.
Purpose: The purpose of this project was to determine the feasibility of employing a functional magnetic resonance imaging (fMRI) task that captured activation associated with overt, unscripted (or free) discourse of people with aphasia (PWA), using a continuous scan paradigm. Method: Seven particip...
| Publicado en: | Journal of Speech, Language & Hearing Research Vol. 66; no. 12; pp. 4838 - 4849 |
|---|---|
| Autores principales: | , , , , , , |
| Formato: | Artículo |
| Publicado: |
American Speech-Language-Hearing Association
Dec2023
|
| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=174209923&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 174209923 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 10924388 1SM jtl: Journal of Speech, Language & Hearing Research issn: 10924388 maglogo: N pubinfo: dt: Dec2023 vid: 66 iid: 12 pid: 42 pub: American Speech-Language-Hearing Association artinfo: ui: 174209923 10.1044/2023_JSLHR-23-00124 ppf: 4838 ppct: 11 formats: fmt: @attributes: type: P size: 776KB tig: atl: Functional Magnetic Resonance Imaging Activation During Unscripted Discourse in People With Poststroke Aphasia. aug: au: Maloney, Thomas C. Dietz, Aimee Vannest, Jennifer Wilkinson, Krista Szaflarski, Jerzy P. Stall, Cassandra Mamlekar, Chitrali R. affil: Department of Radiology, University of Cincinnati, OH Department of Communication Sciences and Disorders, Georgia State University, Atlanta Department of Communication Sciences and Disorders, University of Cincinnati, OH Communication Sciences and Disorders, The Pennsylvania State University, State College Departments of Neurology, Neurobiology, and Neurosurgery, University of Alabama at Birmingham Heersink School of Medicine Speech-Language Pathology Department, Misericordia University, Dallas, PA su: Stroke Paradigms (Social sciences) Sound recordings Diagnosis of aphasia Research Statistics Magnetic resonance imaging Brain mapping Aphasia Comparative studies Inter-observer reliability Photography Descriptive statistics Research funding Data analysis software Statistical correlation Data analysis Medical coding Cerebral cortex Disease complications sug: subj: Stroke Paradigms (Social sciences) Sound recordings Diagnostic Imaging Centers Sound recording merchant wholesalers Integrated Record Production/Distribution Record Production Diagnosis of aphasia Research Statistics Magnetic resonance imaging Brain mapping Aphasia Comparative studies Inter-observer reliability Photography Descriptive statistics Research funding Data analysis software Statistical correlation Data analysis Medical coding Cerebral cortex Disease complications ab: Purpose: The purpose of this project was to determine the feasibility of employing a functional magnetic resonance imaging (fMRI) task that captured activation associated with overt, unscripted (or free) discourse of people with aphasia (PWA), using a continuous scan paradigm. Method: Seven participants (six females, ages 48-70 years) with chronic post-stroke aphasia underwent two fMRI scanning sessions that included a discourse fMRI paradigm that consisted of five 1-min picture description tasks, using personally relevant photographs, interspersed with two 30-s control periods where participants looked at a fixation cross. Audio during the continuous fMRI scan was collected and marked with speaking times and coded for correct information units. Activation maps from the fMRI data were generated for the contrast between speaking and control conditions. In order to show the effects of the multi-echo data analysis, we compared it to a single-echo analysis by using only the middle echo (echo time of 30 ms). Results: Through the implementation of the free discourse fMRI task, we were able to elicit activation that included bilateral regions in the planum polare, central opercular cortex, precentral gyrus, superior temporal gyrus, middle temporal gyrus, superior temporal gyrus, Crus I of the cerebellum, as well as bilateral occipital regions Conclusions: We describe a new tool for assessing discourse recovery in PWA. By demonstrating the feasibility of a natural language paradigm in patients with chronic, poststroke aphasia, we open a new area for future research. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
|---|