Cannabis use disorder and adverse cardiovascular outcomes: A population‐based retrospective cohort analysis of adults from Alberta, Canada.
Aim: To measure the association between cannabis use disorder (CUD) and adverse cardiovascular disease (CVD) outcomes. Design and Setting: We conducted a matched, population‐based retrospective cohort study involving five linked administrative health databases from Alberta, Canada. Participants: We...
| Publicado en: | Addiction Vol. 119; no. 1; pp. 137 - 149 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jan2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=174292869&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 174292869 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09652140 AIO jtl: Addiction issn: 09652140 maglogo: Y pubinfo: dt: Jan2024 vid: 119 iid: 1 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 174292869 172369862 174292869 174292869 10.1111/add.16337 174292869 ppf: 137 ppct: 12 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Cannabis use disorder and adverse cardiovascular outcomes: A population‐based retrospective cohort analysis of adults from Alberta, Canada. aug: au: Bahji, Anees Hathaway, Josh Adams, Denise Crockford, David Edelman, E. Jennifer Stein, Michael D. Patten, Scott B. affil: Department of Psychiatry, University of Calgary, Calgary AB,, Canada sug: subj: Cannabis Canada Substance Use Disorders Diagnosis Cardiovascular Diseases Complications Major Adverse Cardiac Events Outcomes (Health Care) Human Retrospective Design Prospective Studies Social Class Drugs, Prescription Therapeutic Use Poisson Distribution Survival Analysis Relative Risk Confidence Intervals Canada Adult Adult: 19-44 years ab: Aim: To measure the association between cannabis use disorder (CUD) and adverse cardiovascular disease (CVD) outcomes. Design and Setting: We conducted a matched, population‐based retrospective cohort study involving five linked administrative health databases from Alberta, Canada. Participants: We identified participants with CUD diagnosis codes and matched them to participants without CUD codes by gender, year of birth and time of presentation to the health system. We included 29 764 pairs (n = 59 528 individuals in total). Measurements: CVD events were defined by at least one incident diagnostic code within the study period (1 January 2012–31 December 2019). Covariates included comorbidity, socio‐economic status, prescription medication use and health service use. Using mortality‐censored Poisson regression models, we computed survival analyses for time to incident CVD stratified by CUD status. In addition, we calculated crude and stratified risk ratios (RRs) across various covariates using the Mantel–Haenszel technique. Findings: The overall prevalence of documented CUD was 0.8%. Approximately 2.4% and 1.5% of participants in the CUD and unexposed groups experienced an incident adverse CVD event (RR = 1.57; 95% confidence interval = 1.40–1.77). CUD was significantly associated with reduced time to incident CVD event. Individuals who appeared to have greater RRs for incident CVD were those without mental health comorbidity, who had not used health‐care services in the previous 6 months, who were not on prescription medications and who did not have comorbid conditions. Conclusions: Canadian adults with cannabis use disorder appear to have an approximately 60% higher risk of experiencing incident adverse cardiovascular disease events than those without cannabis use disorder. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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