Surgical versus non-surgical treatment of flail chest: a meta-analysis of randomized controlled trials.

Purpose: Conflicting evidence exists on the choice of surgical or non-surgical treatment of flail chest injuries. We aimed to perform a meta-analysis comparing outcomes in patients presenting flail chest undergoing surgical or non-surgical treatment. Methods: Embase, PubMed, and Cochrane databases w...

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Publicado en:European Journal of Trauma & Emergency Surgery Vol. 49; no. 6; pp. 2531 - 2542
Autores principales: Ferreira, Rafael Oliva Morgado, Pasqualotto, Eric, Viana, Patrícia, Schmidt, Pedro Henrique Siedschlag, Andrighetti, Leonardo, Chavez, Matheus Pedrotti, Flausino, Felippe, de Oliveira Filho, Getúlio Rodrigues
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Springer Nature Dec2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Dec2023
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      pub: Springer Nature
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        atl: Surgical versus non-surgical treatment of flail chest: a meta-analysis of randomized controlled trials.
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          Ferreira, Rafael Oliva Morgado
          Pasqualotto, Eric
          Viana, Patrícia
          Schmidt, Pedro Henrique Siedschlag
          Andrighetti, Leonardo
          Chavez, Matheus Pedrotti
          Flausino, Felippe
          de Oliveira Filho, Getúlio Rodrigues
        affil: https://ror.org/041akq887 Federal University of Santa Catarina, R. João Pio Duarte, 144, Córrego Grande, 88037-000, Florianópolis, SC, Brazil
      sug:
        subj:
          Flail Chest Surgery
          Conservative Treatment
          Rib Fractures Complications
          Rib Fractures Surgery
          Emergency Medicine
          Thoracic Injuries Complications
          Treatment Outcomes
          Meta Analysis
          Systematic Review
          Embase
          PubMed
          Cochrane Library
          Confidence Intervals
          Respiration, Artificial
          Length of Stay
          Intensive Care Units
          Pneumonia
          Tracheostomy
          Fracture Fixation
          Human
          Male
          Female
          Adult
          Middle Age
          Data Analysis Software
          Descriptive Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Purpose: Conflicting evidence exists on the choice of surgical or non-surgical treatment of flail chest injuries. We aimed to perform a meta-analysis comparing outcomes in patients presenting flail chest undergoing surgical or non-surgical treatment. Methods: Embase, PubMed, and Cochrane databases were searched for randomized controlled trials (RCTs) comparing surgery to no surgery in patients with acute unstable chest wall injuries. We computed weighted mean differences (WMDs) for continuous outcomes and risk ratios (RRs) for binary endpoints, with 95% confidence intervals (CIs). Random effects meta-analyses were performed. Heterogeneity was assessed using I2 statistics. Results: Six RCTs (544 patients) were included, and surgical treatment was used in 269 (49.4%). Compared to no surgery, surgery reduced mechanical ventilation days (WMD − 4.34, 95% CI – 6.98, − 1.69; p < 0.01; I2 = 87%; GRADE: very low; PI − 13.51, 4.84); length of intensive care unit stay (WMD − 4.62, 95% CI − 7.19, − 2.05; p < 0.01; I2 = 78%; GRADE: low; PI − 12.86, 3.61) and the incidence of pneumonia (RR 0.50, 95% CI 0.31, 0.81; p = 0.005; I2 = 54%; GRADE: moderate; PI 0.13, 1.91). No difference in mortality (RR 0.56, 95% CI 0.19, 1.65; p = 0.27; I2 = 23%; GRADE: moderate; PI 0.04, 7.25), length of hospital stay (WMD − 5.39, 95% CI − 11.38, − 0.60; p = 0.08; I2 = 89%; GRADE: very low; PI − 11.38, 0.60), or need for tracheostomy (RR 0.59, 95% CI 0.34, 1.03; p = 0.06; I2 = 54%; GRADE: moderate; PI 0.11, 3.24) was found. Conclusions: Our results suggest that surgical treatment is advantageous compared to non-surgical treatment for patients with flail chest secondary to rib fractures.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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