Olfactory Dysfunction Associated with Cognitive Decline in an Elderly Population.

In many neurological disorders, including Alzheimer disease, early olfactory dysfunction is observed. In order to determine if deficits in olfactory memory are present in the elderly and if olfactory dysfunction correlates with cognitive impairment in the aging population, olfactory testing has been...

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Published in:Experimental Aging Research Vol. 50; no. 1; pp. 1 - 17
Main Authors: Alotaibi, Majed, Lessard-Beaudoin, Melissa, Busch, Kate, Loudghi, Amal, Gaudreau, Pierrette, Graham, Rona K
Format: research tables/charts Journal Article
Published: Taylor & Francis Ltd Jan/Feb2024
Online Access:View this record in EBSCOhost
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      dt: Jan/Feb2024
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      pub: Taylor & Francis Ltd
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        10.1080/0361073X.2022.2160597
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        atl: Olfactory Dysfunction Associated with Cognitive Decline in an Elderly Population.
      aug:
        au:
          Alotaibi, Majed
          Lessard-Beaudoin, Melissa
          Busch, Kate
          Loudghi, Amal
          Gaudreau, Pierrette
          Graham, Rona K
        affil: King Abdullah International Medical Research Center, KSAU-HS, Riyadh, Saudi Arabia
      sug:
        subj:
          Olfaction Disorders Complications
          Cognition Disorders Risk Factors
          Risk Assessment
          Human
          Male
          Female
          Aged
          Aged, 80 and Over
          Canada
          Scales
          Psychological Tests
          Interviews
          Correlational Studies
          Sex Factors
          Smoking
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: In many neurological disorders, including Alzheimer disease, early olfactory dysfunction is observed. In order to determine if deficits in olfactory memory are present in the elderly and if olfactory dysfunction correlates with cognitive impairment in the aging population, olfactory testing has been done on seniors from the NuAge cohort accepting to participate in the Olfactory Response Cognition and Aging (ORCA) secondary sub-study. The t-Mini Mental Statement Examination and the Telephone Interview for Cognitive Status tests were done to assess cognition levels. Overall, 94% of the ORCA cohort displayed olfactory dysfunction. Deficits in olfactory memory were also present. A correlation was observed between olfactory function and cognitive test scores. Moreover, in women who smoked, there was an association between olfactory memory and cognitive scores. Our results suggest that olfactory dysfunction may predict impending cognitive decline and highlights the need for olfactory training in seniors to improve olfaction and overall well-being.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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