Impact of Tobacco Use on 30-Day Mortality in Subjects Presenting with Spontaneous Intracerebral Hematoma: Retrospective Analysis of 335 Subjects.

Introduction: Spontaneous intracerebral hematoma (ICH) causes significant morbidity and mortality. Risk factors for early mortality still need to be clearly elucidated. This study aimed to identify factors associated with 30-day mortality, hematoma volume, and the presence of intravascular hematoma...

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Published in:Lokman Hekim Health Sciences Vol. 3; no. 2; pp. 132 - 140
Main Authors: Gülensoy, Esen Sayın, Gülensoy, Bülent
Format: research tables/charts Journal Article
Published: KARE Publishing 2023
Online Access:View this record in EBSCOhost
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      dt: 2023
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      pub: KARE Publishing
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        10.14744/lhhs.2022.11001
        174399364
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        atl: Impact of Tobacco Use on 30-Day Mortality in Subjects Presenting with Spontaneous Intracerebral Hematoma: Retrospective Analysis of 335 Subjects.
      aug:
        au:
          Gülensoy, Esen Sayın
          Gülensoy, Bülent
        affil: Department of Chest Diseases, Ufuk University Faculty of Medicine, Ankara, Türkiye
      sug:
        subj:
          Smoking
          Hematoma Mortality
          Cerebral Hemorrhage Mortality
          Risk Assessment
          Cerebral Hemorrhage Prognosis
          Human
          Retrospective Design
          Record Review
          Male
          Female
          Middle Age
          Aged
          Non-Smokers
          Glasgow Coma Scale
          Scales
          Multiple Logistic Regression
          Odds Ratio
          Confidence Intervals
          Intensive Care Units
          Inpatients
          Disease Attributes
          Data Analysis Software
          Descriptive Statistics
          Unpaired T-Tests
          Mann-Whitney U Test
          Fisher's Exact Test
          Linear Regression
          Logistic Regression
          Multiple Linear Regression
          Comparative Studies
          Models, Statistical
          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Introduction: Spontaneous intracerebral hematoma (ICH) causes significant morbidity and mortality. Risk factors for early mortality still need to be clearly elucidated. This study aimed to identify factors associated with 30-day mortality, hematoma volume, and the presence of intravascular hematoma in subjects presenting with spontaneous ICH. Methods: All consecutive subjects (>18 years) admitted to the intensive care unit between January 2013 and June 2021 with spontaneous ICH were analyzed retrospectively. Detailed systemic and neurological examinations were recorded and evaluated from files. Results: A total of 335 subjects (51.3% male, median age 68 [55-77] years) with ICH were included in the study. Of these, 230 were smokers (68.7%), 105 were nonsmokers (31.3%). Compared to nonsmokers, smokers had a lower Glasgow Coma Scale score (p=0.036), larger hematoma volume (p=0.034), higher frequency of intraventricular hematoma (p=0.013). Multiple logistic regression revealed that smokers had 2.069-fold higher risk of death than nonsmokers (OR: 2.069, 95% CI: 1.115-3.839, p=0.021). Smoking was also independently associated with the presence of intraventricular hematoma (OR: 1.669, 95% CI: 1.027-2.711, p=0.039). Discussion and Conclusion: The study showed that smokers have a 2.069-fold greater risk of 30-day mortality and a 1.669-fold higher likelihood of having intraventricular hematoma following spontaneous ICH than nonsmokers.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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