The Clinical Utility of FLT3 Mutation Testing in Acute Leukemia: A Canadian Consensus.
FMS-like tyrosine kinase 3 (FLT3) mutations are detected in approximately 20–30% of patients with acute myeloid leukemia (AML), with the presence of a FLT3 internal tandem duplication (FLT3-ITD) mutation being associated with an inferior outcome. Assessment of FLT3 mutational status is now essential...
| Publicado en: | Current Oncology Vol. 30; no. 12; pp. 10410 - 10437 |
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| Autores principales: | , , , , , , , |
| Formato: | Journal Article |
| Publicado: |
MDPI
Dec2023
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| Acceso en línea: | Ver este registro en EBSCOhost |