A characteristic of olfactory function in four types of dementia and non‐dementia subjects using smell identification test.
Background: For those outpatients who were consulted for memory loss, the Japanese version of University of Pennsylvania Smell Identification Test (UPSIT‐J) was performed to examine olfactory function. In the same way, the revised version of Hasegawa Dementia Scale, Mini Mental State Examination, Cl...
| Publicado en: | Psychogeriatrics Vol. 24; no. 1; pp. 25 - 35 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jan2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=174563633&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 174563633 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13463500 Q4N jtl: Psychogeriatrics issn: 13463500 maglogo: Y pubinfo: dt: Jan2024 vid: 24 iid: 1 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 174563633 173595625 174563633 174563633 10.1111/psyg.13036 174563633 ppf: 25 ppct: 10 formats: tig: atl: A characteristic of olfactory function in four types of dementia and non‐dementia subjects using smell identification test. aug: au: Yamashita, Yuuji Shoji, Yoshihisa Yanagimoto, Hiroko Morita, Kiichiro Kodama, Hideya Tsuruhisa, Yuuki Ookawa, Junji affil: Cognitive and Molecular Research Institute of Brain Diseases, Kurume University, Kurume, Japan sug: subj: Dementia Classification Smell Evaluation Smell Physiology Dementia Diagnosis Early Diagnosis Dementia Patients Human Funding Source Alzheimer's Disease Dementia, Vascular Lewy Body Disease Mixed Dementias Scales Correlation Coefficient Descriptive Statistics Aged Aged, 80 and Over Odors Aged: 65+ years Aged, 80 & over ab: Background: For those outpatients who were consulted for memory loss, the Japanese version of University of Pennsylvania Smell Identification Test (UPSIT‐J) was performed to examine olfactory function. In the same way, the revised version of Hasegawa Dementia Scale, Mini Mental State Examination, Clinical Dementia Rating and brain magnetic resonance imaging were used to investigate the cognitive function. In the present study, we evaluated the olfactory function of elderly subjects, including those with dementia, by means of UPSIT‐J and we examined their characteristics. Methods: The characteristics of dementia as Alzheimer type group (AD.G), mixed type group (MixD.G), vascular type group (VaD.G), dementia with Lewy bodies group (DLB.G) and the groups which had no dementia as low score group (LS.G), high score group (HS.G), and healthy group (H.G), were examined. Results: The numbers of olfactory discriminating scores (nODS) were significantly lower in all the dementia groups than in all the LS.G, HS.G and the H.G. No significant difference was observed in nODS between AD.G and DLB.G. The rate of nODS with less than five scores were as follows: AD.G (80.1%), MixD.G (91.5%), VaD.G (63.1%), DLB.G (89.6%), LS.G (50.8%), HS.G (18.6%), H.G (15.6%). A significant positive correlation was found between nODS and Hasegawa Dementia Scale and Mini Mental State Examination scores (r = 0.567, r = 0.532, respectively), which was significant negatively correlated for Clinical Dementia Rating (r = −0.578). A significant negative correlation was observed between nODS and Z score of voxel‐based specific regional analysis for Z score of Alzheimer's disease (VSRAD) (r = 0.463). Conclusion: nODS showed a significant correlation between cognitive function tests and brain atrophy level. These results indicate that UPSIT‐J is considered a psycho‐physiological index useful for the diagnosis and early detection of dementia. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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