Contribution of Transcutaneous ... in Obesity Hypoventilation Syndrome.
BACKGROUND: More and more patients have obesity-hypoventilation syndrome (OHS) because of the increasing prevalence of obesity. The accuracy of transcutaneous ... has recently been validated. However, no study evaluated the interest of measuring systematically nocturnal ... in the follow-up of patie...
| Published in: | Respiratory Care Vol. 69; no. 1; pp. 68 - 76 |
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| Main Authors: | , , , , , , , |
| Format: | research tables/charts Journal Article |
| Published: |
Mary Ann Liebert, Inc.
Jan2024
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=174595775&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 174595775 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Jan2024 vid: 69 iid: 1 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 174595775 174595775 174595775 10.4187/respcare.10816 174595775 ppf: 68 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Contribution of Transcutaneous ... in Obesity Hypoventilation Syndrome. aug: au: Georges, Thomas Jaffré, Sandrine Morin, Jean Delbove, Agathe Guyomarch, Béatrice Alami, Hakim Bretonnière, Cédric Blanc, François-Xavier affil: Respiratory Medicine Department, CHD Vendée, La Roche sur Yon, France sug: subj: Pickwickian Syndrome Physiopathology Hypoventilation Physiopathology Blood Gas Monitoring, Transcutaneous Methods Pulmonary Gas Exchange Evaluation Pulse Oximetry Evaluation Human Male Female Middle Age Aged Prospective Studies Pilot Studies Home Oxygen Therapy Methods Capnography Methods Fisher's Exact Test Mann-Whitney U Test Data Analysis Software Descriptive Statistics Middle Aged: 45-64 years Aged: 65+ years Male Female ab: BACKGROUND: More and more patients have obesity-hypoventilation syndrome (OHS) because of the increasing prevalence of obesity. The accuracy of transcutaneous ... has recently been validated. However, no study evaluated the interest of measuring systematically nocturnal ... in the follow-up of patients with OHS and home mechanical ventilation to detect residual nocturnal hypoventilation. We aimed to evaluate the contribution of nocturnal ... to assess nocturnal hypoventilation compared with current routine examinations, that is, daytime arterial blood gases and nocturnal pulse oximetry. METHODS: A prospective monocentric pilot study was conducted from August 2018 to November 2019. Patients with stable OHS and who were treated with home noninvasive ventilation for at least 6 months were eligible to participate. After oral consent, we performed both diurnal arterial blood gases and combined home oximetry and capnography. The primary end point was the presence of residual nocturnal hypoventilation, defined as ... > 45 mm Hg or bicarbonate ≥ 27 mmol/L, ... < 90% for ≥ 10% of the night, or ... > 49 mm Hg for ≥ 10% of the night. RESULTS: A total of 32 subjects were included. Twenty-nine subjects with nocturnal ... were analyzed. Eighteen of the 29 subjects showed residual nocturnal hypoventilation. The association of diurnal arterial blood gases and nocturnal pulse oximetry revealed nocturnal hypoventilation in only 9 subjects. Among the 19 subjects with both normal blood gases and normal nocturnal pulse oximetry, 11 had nocturnal hypoventilation with transcutaneous capnography. Only one subject presented with hypoventilation symptoms (asthenia). CONCLUSIONS: The assessment of ... in comparison with nocturnal pulse oximetry and arterial blood gases provides important information for the diagnosis of residual nocturnal hypoventilation in the subjects with OHS who were ventilated at home. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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