An evaluation of naloxone transit for opioid overdose using drones: A case study using real‐world coroner data.

Background and aims: Opioids are now the most cited class in fatal overdoses. However, the antidote for opioid overdose—naloxone—is not always readily available. Our aim was to evaluate the feasibility of naloxone transit via drone to provide rapid access at the point of care. Methods and findings:...

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Publicado en:Addiction Vol. 119; no. 2; pp. 379 - 386
Autores principales: Royall, Paul G., Courtney, Patrick, Goodair, Christine, Copeland, Caroline S.
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell Feb2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2024
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: An evaluation of naloxone transit for opioid overdose using drones: A case study using real‐world coroner data.
      aug:
        au:
          Royall, Paul G.
          Courtney, Patrick
          Goodair, Christine
          Copeland, Caroline S.
        affil: Centre for Pharmaceutical Medicine Research, Institute of Pharmaceutical Science, King's College London, London, UK
      sug:
        subj:
          Overdose Drug Therapy
          Naloxone Therapeutic Use
          Drone Aircraft Utilization
          Analgesics, Opioid Adverse Effects
          Health Services Accessibility Evaluation
          Emergency Medical Services Evaluation
          Reaction Time Evaluation
          Human
          United Kingdom
          Case Studies
          Ambulances
          Time Factors
          Chi Square Test
          Data Analysis Software
          Descriptive Statistics
      ab: Background and aims: Opioids are now the most cited class in fatal overdoses. However, the antidote for opioid overdose—naloxone—is not always readily available. Our aim was to evaluate the feasibility of naloxone transit via drone to provide rapid access at the point of care. Methods and findings: Real‐world data pertaining to opioid overdoses, which occurred in the Teesside area of the UK 2015–2019, were extracted from the National Programme on Substance Abuse Deaths (NPSAD). The original locations of these opioid overdoses were used to compare the projected response times of ambulances with that of drones when considering the impacts of actual traffic and weather conditions, respectively; 58 cases were identified where a bystander—who could have called for and administered emergency naloxone—was likely present. Results: In 78% of cases (n = 45/58) a class C1 commercial‐off‐the‐shelf drone carrying naloxone could have reached the overdose location in 7 min—the benchmark time for the arrival of emergency services for Category 1 calls in England. With the implementation of recent advances in drone engineering, such as increased speeds and temperature‐controlled cargo cradles, it is estimated that 98% of overdoses could have been reached in this timeframe (n = 57/58). Ambulances were able to reach a significantly lower number of cases in 7 min, even when considering best‐case scenario traffic conditions (14%, n = 8/58, χ2P < 0.001). Conclusions: This study provides proof‐of‐concept that, in the Teesside area of the UK, drones are more likely than ambulance to get naloxone to the site of an opioid overdose in 7 min.
      pubtype: Academic Journal
      doctype:
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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