Could Sensory Differences Be a Sex-Indifferent Biomarker of Autism? Early Investigation Comparing Tactile Sensitivity Between Autistic Males and Females.

Sensory differences are highly prevalent in autistic individuals. However, few studies have compared their presentation between autistic males and autistic females. We used psychophysics to assess and compare tactile perceptual sensitivity between autistic and non-autistic boys and girls aged betwee...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 54; no. 1; pp. 239 - 256
Autores principales: Asaridou, Magdalini, Wodka, Ericka L., Edden, Richard A. E., Mostofsky, Stewart H., Puts, Nicolaas A. J., He, Jason L.
Formato: pictorial research tables/charts tracings Journal Article
Publicado: Springer Nature Jan2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan2024
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        atl: Could Sensory Differences Be a Sex-Indifferent Biomarker of Autism? Early Investigation Comparing Tactile Sensitivity Between Autistic Males and Females.
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          Asaridou, Magdalini
          Wodka, Ericka L.
          Edden, Richard A. E.
          Mostofsky, Stewart H.
          Puts, Nicolaas A. J.
          He, Jason L.
        affil: https://ror.org/0220mzb33 Social, Genetic and Developmental Psychiatric Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
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          Autism Spectrum Disorder Diagnosis
          Touch Evaluation
          Sex Factors
          Biological Markers
          Men
          Women
          Early Diagnosis
          Psychophysics
          Human
          Male
          Female
          Child
          Comparative Studies
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          Clinical Assessment Tools
          Interview Guides
          Neuropsychological Tests
          Scales
          Funding Source
          Child: 6-12 years
          Male
          Female
      ab: Sensory differences are highly prevalent in autistic individuals. However, few studies have compared their presentation between autistic males and autistic females. We used psychophysics to assess and compare tactile perceptual sensitivity between autistic and non-autistic boys and girls aged between 8 and 12 years of age. While there were sex-differences of amplitude discrimination, frequency discrimination and order judgement thresholds, these sex-differences were not autism-specific. Mean RTs and detection thresholds were elevated in autism but were comparable between the sexes. Tactile sensitivity measures that are elevated in autism but are otherwise comparable between autistic males and autistic females suggest the possibility that certain sensory features could be used as sex-indifferent markers of autism. Further investigation with larger and more representative samples should be conducted before any stronger conclusions are made.
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    language: English
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