Agreement between cause of death assignment by computer-coded verbal autopsy methods and physician coding of verbal autopsy interviews in South Africa.

The South African national cause of death validation (NCODV 2017/18) project collected a national sample of verbal autopsies (VA) with cause of death (COD) assignment by physician-coded VA (PCVA) and computer-coded VA (CCVA). The performance of three CCVA algorithms (InterVA-5, InSilicoVA and Tariff...

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Publicado en:Global Health Action Vol. 16; no. 1; pp. 1 - 14
Autores principales: Groenewald, Pam, Thomas, Jason, Clark, Samuel J, Morof, Diane, Joubert, Jané D., Kabudula, Chodziwadziwa, Li, Zehang, Bradshaw, Debbie
Formato: equations & formulas research tables/charts Journal Article
Publicado: Taylor & Francis Ltd 2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2023
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      pub: Taylor & Francis Ltd
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        10.1080/16549716.2023.2285105
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        atl: Agreement between cause of death assignment by computer-coded verbal autopsy methods and physician coding of verbal autopsy interviews in South Africa.
      aug:
        au:
          Groenewald, Pam
          Thomas, Jason
          Clark, Samuel J
          Morof, Diane
          Joubert, Jané D.
          Kabudula, Chodziwadziwa
          Li, Zehang
          Bradshaw, Debbie
        affil: Burden of Disease Research Unit, South African Medical Research Council, Cape Town, South Africa
      sug:
        subj:
          Cause of Death South Africa
          Autopsy Methods
          Algorithms
          Computing Methodologies
          South Africa
          Human
          Funding Source
          Descriptive Statistics
          Data Analysis Software
          Confidence Intervals
          Odds Ratio
          Spearman's Rank Correlation Coefficient
          Mortality
      ab: The South African national cause of death validation (NCODV 2017/18) project collected a national sample of verbal autopsies (VA) with cause of death (COD) assignment by physician-coded VA (PCVA) and computer-coded VA (CCVA). The performance of three CCVA algorithms (InterVA-5, InSilicoVA and Tariff 2.0) in assigning a COD was compared with PCVA (reference standard). Seven performance metrics assessed individual and population level agreement of COD assignment by age, sex and place of death subgroups. Positive predictive value (PPV), sensitivity, overall agreement, kappa, and chance corrected concordance (CCC) assessed individual level agreement. Cause-specific mortality fraction (CSMF) accuracy and Spearman's rank correlation assessed population level agreement. A total of 5386 VA records were analysed. PCVA and CCVAs all identified HIV/AIDS as the leading COD. CCVA PPV and sensitivity, based on confidence intervals, were comparable except for HIV/AIDS, TB, maternal, diabetes mellitus, other cancers, and some injuries. CCVAs performed well for identifying perinatal deaths, road traffic accidents, suicide and homicide but poorly for pneumonia, other infectious diseases and renal failure. Overall agreement between CCVAs and PCVA for the top single cause (48.2–51.6) indicated comparable weak agreement between methods. Overall agreement, for the top three causes showed moderate agreement for InterVA (70.9) and InSilicoVA (73.8). Agreement based on kappa (−0.05–0.49)and CCC (0.06–0.43) was weak to none for all algorithms and groups. CCVAs had moderate to strong agreement for CSMF accuracy, with InterVA-5 highest for neonates (0.90), Tariff 2.0 highest for adults (0.89) and males (0.84), and InSilicoVA highest for females (0.88), elders (0.83) and out-of-facility deaths (0.85). Rank correlation indicated moderate agreement for adults (0.75–0.79). Whilst CCVAs identified HIV/AIDS as the leading COD, consistent with PCVA, there is scope for improving the algorithms for use in South Africa.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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