Optimizing Gene Selection and Cancer Classification with Hybrid Sine Cosine and Cuckoo Search Algorithm.

Gene expression datasets offer a wide range of information about various biological processes. However, it is difficult to find the important genes among the high-dimensional biological data due to the existence of redundant and unimportant ones. Numerous Feature Selection (FS) techniques have been...

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Publicado en:Journal of Medical Systems Vol. 48; no. 1; pp. 1 - 19
Autores principales: Yaqoob, Abrar, Verma, Navneet Kumar, Aziz, Rabia Musheer
Formato: algorithm equations & formulas tables/charts Journal Article
Publicado: Springer Nature 1/9/2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 1/9/2024
      vid: 48
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      pid: 237
      pub: Springer Nature
      place: New York, New York
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        10.1007/s10916-023-02031-1
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        atl: Optimizing Gene Selection and Cancer Classification with Hybrid Sine Cosine and Cuckoo Search Algorithm.
      aug:
        au:
          Yaqoob, Abrar
          Verma, Navneet Kumar
          Aziz, Rabia Musheer
        affil: https://ror.org/02ax13658 School of Advanced Sciences and Languages, VIT Bhopal University, 466114, Kothrikalan, Sehore, India
      sug:
        subj:
          Gene Expression
          Neoplasms Classification
          Algorithms
          Machine Learning
          Support Vector Machine
          Birds
          Technology Utilization
          Gene Expression Profiling
          Confounding Variable
          Information Resources
          Information Science Methods
          Models, Theoretical
          Quality Improvement
      ab: Gene expression datasets offer a wide range of information about various biological processes. However, it is difficult to find the important genes among the high-dimensional biological data due to the existence of redundant and unimportant ones. Numerous Feature Selection (FS) techniques have been created to get beyond this obstacle. Improving the efficacy and precision of FS methodologies is crucial in order to identify significant genes amongst complicated complex biological data. In this work, we present a novel approach to gene selection called the Sine Cosine and Cuckoo Search Algorithm (SCACSA). This hybrid method is designed to work with well-known machine learning classifiers Support Vector Machine (SVM). Using a dataset on breast cancer, the hybrid gene selection algorithm's performance is carefully assessed and compared to other feature selection methods. To improve the quality of the feature set, we use minimum Redundancy Maximum Relevance (mRMR) as a filtering strategy in the first step. The hybrid SCACSA method is then used to enhance and optimize the gene selection procedure. Lastly, we classify the dataset according to the chosen genes by using the SVM classifier. Given the pivotal role gene selection plays in unraveling complex biological datasets, SCACSA stands out as an invaluable tool for the classification of cancer datasets. The findings help medical practitioners make well-informed decisions about cancer diagnosis and provide them with a valuable tool for navigating the complex world of gene expression data.
      pubtype: Academic Journal
      doctype:
        algorithm
        equations & formulas
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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