The association between frailty and perceived physical and mental fatigability: The Long Life Family Study.
Background: Higher levels of frailty, quantified by a frailty index (FI), may be linked to fatigue severity as tasks become more physically and mentally demanding. Fatigue, a component of frailty research, has been ambiguous and inconsistent in its operationalization. Fatigability—the quantification...
| Publicado en: | Journal of the American Geriatrics Society Vol. 72; no. 1; pp. 219 - 226 |
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| Autores principales: | , , , , , , , , , , , |
| Formato: | Artículo |
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Wiley-Blackwell
Jan2024
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| Materias: | |
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=174911947&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 174911947 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 00028614 20Q jtl: Journal of the American Geriatrics Society issn: 00028614 maglogo: Y pubinfo: dt: Jan2024 vid: 72 iid: 1 pid: 480 pub: Wiley-Blackwell artinfo: ui: 174911947 10.1111/jgs.18624 ppf: 219 ppct: 7 formats: tig: atl: The association between frailty and perceived physical and mental fatigability: The Long Life Family Study. aug: au: Schumacher, Benjamin T. Kehler, Dustin S. Kulminski, Alexander M. Qiao, Yujia Andersen, Stacy L. Gmelin, Theresa Christensen, Kaare Wojczynski, Mary K. Theou, Olga Rockwood, Kenneth Newman, Anne B. Glynn, Nancy W. affil: Department of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh Pennsylvania,, USA School of Physiotherapy, Dalhousie University, Halifax Nova Scotia,, Canada Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham North Carolina,, USA Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston Massachusetts,, USA Danish Aging Research Center, University of Southern Denmark, Odense, Denmark Departments of Clinical Biochemistry and Clinical Genetics, Odense University Hospital, Odense, Denmark School of Medicine, Washington University, St. Louis Missouri,, USA Division of Geriatric Medicine, Department of Medicine, Dalhousie University, Halifax Nova Scotia,, Canada su: Cross-sectional method Task performance White people Old age Frail elderly Confidence intervals Physical activity Risk assessment Severity of illness index Research funding Descriptive statistics Fatigue (Physiology) Medical appointments Mental fatigue sug: subj: Cross-sectional method Task performance White people Old age Frail elderly Confidence intervals Physical activity Risk assessment Severity of illness index Research funding Descriptive statistics Fatigue (Physiology) Medical appointments Mental fatigue keyword: epidemiology fatigue risk factor epidemiology fatigue risk factor ab: Background: Higher levels of frailty, quantified by a frailty index (FI), may be linked to fatigue severity as tasks become more physically and mentally demanding. Fatigue, a component of frailty research, has been ambiguous and inconsistent in its operationalization. Fatigability—the quantification of vulnerability to fatigue in relation to specific intensity and duration of activities—offers a more sensitive and standardized approach, though the association between frailty and fatigability has not been assessed. Methods: Using cross‐sectional data from the Long Life Family Study at Visit 2 (2014–2017; N = 2524; mean age ± standard deviation (SD) 71.4 ± 11.2 years; 55% women; 99% White), we examined associations between an 83‐item FI after excluding fatigue items (ratio of number of health problems reported (numerator) out of the total assessed (denominator); higher ratio = greater frailty) and perceived physical and mental fatigability using the Pittsburgh Fatigability Scale (PFS) (range 0–50; higher scores = greater fatigability). Results: Participants had mean ± standard deviation FI (0.08 ± 0.06; observed range: 0.0–0.43), PFS Physical (13.7 ± 9.6; 39.5% more severe, ≥15), and PFS Mental (7.9 ± 8.9; 22.8% more severe, ≥13). The prevalence of more severe physical and mental fatigability was higher across FI quartiles. In mixed effects models accounting for family structure, a clinically meaningful 3%‐higher FI was associated with 1.9 points higher PFS Physical score (95% confidence interval (CI) 1.7–2.1) and 1.7 points higher PFS Mental score (95% CI 1.5–1.9) after adjusting for covariates. Conclusions: Frailty was associated with perceived physical and mental fatigability severity. Understanding this association may support the development of interventions to mitigate the risks associated with greater frailty and perceived fatigability. Including measurements of perceived fatigability, in lieu of fatigue, in frailty indices has the potential to alleviate the inconsistencies and ambiguity surrounding the operationalization of fatigue and provide a more precise and sensitive measurement of frailty. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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