Effect of a Conical-PEP Mask on Exercise in Subjects With COPD.

BACKGROUND: Dynamic hyperinflation (DH) is a major pathophysiology of COPD that is directly related to dyspnea and exercise intolerance. Positive expiratory pressure (PEP) might reduce DH and dyspnea during exercise, but at present, there is insufficient evidence to conclude whether it is beneficial...

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Publicado en:Respiratory Care Vol. 69; no. 2; pp. 191 - 202
Autores principales: Chulee Ubolsakka-Jones, Jones, David A., Malipron Pukdeechat, Watchara Boonsawat, Wilaiwan Khrisanapant, Chatchai Phimphasak
Formato: CEU pictorial research tables/charts randomized controlled trial Journal Article
Publicado: Mary Ann Liebert, Inc. Feb2024
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Mary Ann Liebert, Inc.
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        atl: Effect of a Conical-PEP Mask on Exercise in Subjects With COPD.
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          Chulee Ubolsakka-Jones
          Jones, David A.
          Malipron Pukdeechat
          Watchara Boonsawat
          Wilaiwan Khrisanapant
          Chatchai Phimphasak
        affil: School of Physical Therapy, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand
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        subj:
          Pulmonary Disease, Chronic Obstructive
          Masks Evaluation
          Positive End-Expiratory Pressure
          Exercise
          Dyspnea
          Training Effect (Physiology)
          Cardiopulmonary Physiology
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      ab: BACKGROUND: Dynamic hyperinflation (DH) is a major pathophysiology of COPD that is directly related to dyspnea and exercise intolerance. Positive expiratory pressure (PEP) might reduce DH and dyspnea during exercise, but at present, there is insufficient evidence to conclude whether it is beneficial for DH, dyspnea, and exercise capacity in COPD. METHODS: A randomized crossover trial with concealed allocation was conducted in 37 moderate to very severe subjects with COPD (34 males, age 66.6 ± 7.4 y, FEV1% of predicted 56.3 ± 13.7). The experimental condition was conical-PEP breathing with a PEP of around 5 cm H2O during a spot marching exercise at a constant speed, inducing 71 6 9% age-predicted maximum heart rate to symptom limit or 25 min. The control condition was usual breathing. Exercise endurance time and end-exercise symptoms were recorded. Inspiratory capacity (IC) was measured pre-exercise and immediately post exercise. Cardiopulmonary function and breathlessness were monitored throughout the test and after 10 min of recovery. RESULTS: There were no complications or adverse effects during exercise with a conical-PEP mask. Conical-PEP showed longer exercise times than control (median 11.0 [interquartile range 7.7-17.0] min vs 8 [6.0-11.5] min, respectively, P < .001). Most stopped exercising because of breathlessness and leg fatigue. At the end of exercise, IC and breathlessness showed non-significant differences between the conditions, but breathlessness was significantly lower in conical-PEP (median 4 [1.5-5.0] than control 5 [3-6] on Borg scale at isotime for control [8 min]). CONCLUSIONS: Breathing with a 5 cm H2O conical-PEP mask improved exercise time (median 27.1% [0.6-52.9]) in subjects with COPD. The improvement in exercise with the conical-PEP mask was associated with slower development of breathlessness, possibly due to delays in DH development.
      pubtype: Academic Journal
      doctype:
        CEU
        pictorial
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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