Factors affecting quality of life in adults with HIV: A local cross-sectional study.

Background: Understanding health-related quality of life (HRQOL) among people with HIV (PWH) can inform strategies to maintain or improve health and functioning. Most HRQOL research has focused on resource-rich settings, underrepresenting younger cohorts in lowresource settings. Objectives: To asses...

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Publicado en:South African Journal of Physiotherapy Vol. 79; no. 1; pp. 1 - 14
Autores principales: Berner, Karina, Louw, Quinette A.
Formato: research tables/charts Journal Article
Publicado: African Online Scientific Information System PTY LTD 2023
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2023
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        atl: Factors affecting quality of life in adults with HIV: A local cross-sectional study.
      aug:
        au:
          Berner, Karina
          Louw, Quinette A.
        affil: Department of Health and Rehabilitation Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
      sug:
        subj:
          Quality of Life Evaluation
          Quality of Life Psychosocial Factors
          HIV-Positive Persons Psychosocial Factors
          Primary Health Care South Africa
          Office Visits
          Human
          Cross Sectional Studies
          South Africa
          Male
          Female
          Questionnaires
          Visual Analog Scaling
          Regression
          Pain
          Depression
          Anxiety
          Activities of Daily Living
          Self Care
          Rising
          Income
          Poverty
          Disease Duration
          HIV Infections Drug Therapy
          Polypharmacy
          Anti-Retroviral Agents Therapeutic Use
          Medication Compliance
          Self Report
          Patient-Reported Outcomes
          Descriptive Research
          Adolescence
          Adult
          Middle Age
          Aged
          Aged, 80 and Over
          Descriptive Statistics
          Funding Source
          Adolescent: 13-18 years
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: Background: Understanding health-related quality of life (HRQOL) among people with HIV (PWH) can inform strategies to maintain or improve health and functioning. Most HRQOL research has focused on resource-rich settings, underrepresenting younger cohorts in lowresource settings. Objectives: To assess HRQOL and associated factors in PWH visiting two primary healthcare clinics in the Western Cape, South Africa. Method: A cross-sectional study included 48 PWH (58.3% women; mean age: 39.2 [10.3]). Health-related QOL was assessed using EQ-5D-5L descriptive domains, visual analogue scale (EQ-VAS), and index score (EQ-index). Mobility was assessed using clinical tests. Tobit regression determined associations. Results: Mean and median EQ-VAS scores were 88.14 (16.35) and 95.00. Mean and median EQ-index scores were 0.84 (0.10) and 0.90. PWH reported problems as pain/discomfort (35.4%), depression/anxiety (25.0%), mobility (22.9%), usual activities (18.7%) and self-care (12.5%) domains. Slow chair rise (p = 0.012), low income (p = 0.030), longer HIV duration (p = 0.009) and polypharmacy (p = 0.034) were associated with lower HRQOL. Antiretroviral therapy (ART) adherence was associated with higher HRQOL (p = 0.020). Conclusion: Despite high overall HRQOL, specific domains presented challenges to PWH. Health-related QOL was associated with chair rise repetitions, income, HIV duration, polypharmacy, and treatment adherence. Comprehensive care and contextualised interventions to address these through rehabilitation, including health promotion, are proposed strategies for future investigation. Clinical implications: Clinicians should be cognisant of potential physical and mental functioning problems, and factors related to drug therapy, socio-economic status and disease duration that may affect HRQOL even in seemingly unimpaired PWH.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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