Risk factors for venous ulceration in patients with varicose veins of lower extremities.

The aim of this case–control study was to explore the potential risk factors for venous ulceration in patients with varicose veins of lower extremities and to establish a simplified diagnostic score model. Seventy subjects with varicose veins of lower extremities and venous ulceration were compared...

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Publicado en:Wound Repair & Regeneration Vol. 32; no. 1; pp. 47 - 55
Autores principales: Yin, Chaonan, Tang, Fang, Lao, Jiahui, Yang, Yang, Li, Mingzhuo, Cao, Jia, Song, Ru, Wu, Peng, Wang, Yibing
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Jan/Feb2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan/Feb2024
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/wrr.13139
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        atl: Risk factors for venous ulceration in patients with varicose veins of lower extremities.
      aug:
        au:
          Yin, Chaonan
          Tang, Fang
          Lao, Jiahui
          Yang, Yang
          Li, Mingzhuo
          Cao, Jia
          Song, Ru
          Wu, Peng
          Wang, Yibing
        affil: Department of Plastic Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China
      sug:
        subj:
          Venous Ulcer Risk Factors
          Venous Ulcer Diagnosis
          Varicose Veins Complications
          Lower Extremity Pathology
          Risk Assessment
          Clinical Assessment Tools
          Funding Source
          Human
          Multivariate Analysis
          Multiple Logistic Regression
          Comparative Studies
          Obesity Complications
          Lymphocyte Count
          Fibrinogen Blood
          Male
          ROC Curve
          Case Control Studies
          Female
          Sex Factors
          Disease Duration
          Male
          Female
      ab: The aim of this case–control study was to explore the potential risk factors for venous ulceration in patients with varicose veins of lower extremities and to establish a simplified diagnostic score model. Seventy subjects with varicose veins of lower extremities and venous ulceration were compared with 1164 controls with varicose veins of lower extremities and no history of venous ulceration. Stepwise multivariate logistic regression analysis was used to identify the risk factors for venous ulceration. The steps in developing the diagnostic score model were based on the Framingham Heart study. The area under the receiver operating characteristic curve (AUC) was calculated to assess the diagnostic ability of the diagnostic score model. Multivariate analysis showed that men, overweight, obesity, longer duration varicose veins, deep venous valve insufficiency, low lymphocyte counts, and high fibrinogen content were independently associated with an increased risk of venous ulceration. The AUC for the diagnostic score model was 0.75, which indicated good discriminatory ability. Special attention should be paid to the high‐risk group of patients with lower extremity varicose veins. The diagnostic score model might be a useful screening tool for clinicians, policy makers, and patients.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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