Echocardiographic parameters associated with less reverse left ventricular remodeling after transcatheter aortic valve implant in subjects with prosthesis patient mismatch.
Background: Transaortic valve implant (TAVI) is the treatment of choice for severe aortic stenosis (AS). Some patients develop prosthesis patient mismatch (PPM) after TAVI. It is challenging to determine which patients are at risk for clinical deterioration. Methods: We retrospectively measured echo...
| Publicado en: | Echocardiography Vol. 41; no. 1; pp. 1 - 11 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | diagnostic images research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jan2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=175071896&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 175071896 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 07422822 GSE jtl: Echocardiography issn: 07422822 maglogo: Y pubinfo: dt: Jan2024 vid: 41 iid: 1 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 175071896 175071896 175071896 10.1111/echo.15698 175071896 ppf: 1 ppct: 10 formats: fmt: – @attributes: type: T – @attributes: type: C – @attributes: type: P tig: atl: Echocardiographic parameters associated with less reverse left ventricular remodeling after transcatheter aortic valve implant in subjects with prosthesis patient mismatch. aug: au: Peters, Andrew C. Gong, Fei Fei Ramesh, Ashvita Andrei, Adin Jankowski, Madeline Cantey, Eric Chen, Vincent Thomas, James D. Flaherty, James D. Malaisrie, S. Christopher Maganti, Kameswari affil: Northwestern University Feinberg School of Medicine, Chicago, USA sug: subj: Aortic Valve Stenosis Surgery Transcatheter Aortic Valve Implantation Adverse Effects Ventricular Function, Left Physiology Ventricular Remodeling Echocardiography Heart Valve Prosthesis Utilization Treatment Outcomes Geriatric Functional Assessment Human Male Female Aged Aged, 80 and Over Retrospective Design Aortic Valve Insufficiency Descriptive Statistics Comparative Studies Aortic Valve Stenosis Ultrasonography Correlation Coefficient Data Analysis Software Clinical Assessment Tools Functional Status Survival Rate Aged: 65+ years Aged, 80 & over Male Female ab: Background: Transaortic valve implant (TAVI) is the treatment of choice for severe aortic stenosis (AS). Some patients develop prosthesis patient mismatch (PPM) after TAVI. It is challenging to determine which patients are at risk for clinical deterioration. Methods: We retrospectively measured echocardiographic parameters of left ventricular (LV) morphology and function, prosthetic aortic valve effective orifice area (iEOA) and hemodynamics in 313 patients before and 1 year after TAVI. Our objective was to compare the change in echocardiographic parameters associated with left ventricular reverse modeling in subjects with and without PPM. Our secondary objective was to evaluate echo parameters associated with PPM and the relationship to patient functional status and survival post‐TAVI. Results: We found that 82 (26.2%) of subjects had moderate and 37 (11.8%) had severe PPM post‐TAVI. There was less relative improvement in LVEF with PPM (1.9 ± 21.3% vs. 8.2 + 30.1%, p =.045). LV GLS also exhibited less relative improvement in those with PPM (13.4 + 34.1% vs. 30.9 + 73.3%, p =.012). NYHA functional class improved in 84.3% of subjects by one grade or more. Echocardiographic markers of PPM were worse in those without improvement in NYHA class (mean AT/ET was.29 vs..27, p =.05; DVI was.46 vs..51, p =.021; and iEOA was.8 cm/m2 vs..9 cm/m2, p =.025). There was no association with PPM and survival. Conclusions: There was no improvement in LVEF and less improvement in LV GLS in those with PPM post‐TAVI. Echocardiographic markers of PPM were present in those with lack of improvement in NYHA functional class. pubtype: Academic Journal doctype: diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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