Validity of an automated screening Dixon technique for quantifying hepatic steatosis in living liver donors.
Purpose: This retrospective study aimed to evaluate the validity of an automated screening Dixon (e-DIXON) technique for quantifying hepatic steatosis in living liver-donor patients by comparison with magnetic resonance spectroscopy (MRS) as a reference standard. Methods: A total of 285 living liver...
| Publicado en: | Abdominal Radiology Vol. 49; no. 2; pp. 406 - 414 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
Feb2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=175163308&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 175163308 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 2366004X JT14 jtl: Abdominal Radiology issn: 2366004X maglogo: N pubinfo: dt: Feb2024 vid: 49 iid: 2 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 175163308 173359425 10.1007/s00261-023-04009-6 175163308 ppf: 406 ppct: 8 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Validity of an automated screening Dixon technique for quantifying hepatic steatosis in living liver donors. aug: au: Song, Sangkeun Kim, Hokun Choi, Joon-Il Kim, Dong Hwan Kim, Bohyun Lee, Hyunsoo Lee, Jiwon affil: Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, 06591, Seoul, Republic of Korea sug: ab: Purpose: This retrospective study aimed to evaluate the validity of an automated screening Dixon (e-DIXON) technique for quantifying hepatic steatosis in living liver-donor patients by comparison with magnetic resonance spectroscopy (MRS) as a reference standard. Methods: A total of 285 living liver-donor candidates were examined with the e-DIXON technique and single-voxel MRS to assess hepatic steatosis and iron deposition between January 2014 and February 2019. The sensitivity, specificity, and positive and negative predictive values (PPV and NPV) of the e-DIXON technique for hepatic steatosis were calculated. The mean fat signal fractions obtained in MRS were compared between the donors diagnosed with hepatic steatosis and the normal group. The mean R2 values of donors with or without hepatic siderosis also were compared. Results: The e-DIXON technique diagnosed normal in 133 (47%), fat in 124 (44%), iron in one (0.4%), and a combination of both fat and iron in 27 (10%) donors. The sensitivity, specificity, PPV, and NPV for diagnosing hepatic steatosis were 94%, 70%, 64%, and 96%, respectively. There was a significant difference in the mean fat signal fraction obtained in MRS between the steatosis and normal groups (p < 0.001), but R2 values were not significantly different between siderosis and normal groups (p = 0.11). The e-DIXON technique showed a strong correlation with MRS in fat measurement (r2 = 0.92, p < 0.001). Conclusion: The e-DIXON technique reliably screens for hepatic steatosis but may not accurate for detecting hepatic iron deposition. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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