Novel attentional gait index reveals a cognitive ability-related decline in gait automaticity during dual-task walking.

Introduction: Gait automaticity refers to the ability to walk with minimal recruitment of attentional networks typically mediated through the prefrontal cortex (PFC). Reduced gait automaticity (i.e., greater use of attentional resources during walking) is common with aging, contributing to an increa...

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Publicado en:Frontiers in Aging Neuroscience pp. 1 - 14
Autores principales: Shuqi Liu, Rosso, Andrea L., Baillargeon, Emma M., Weinstein, Andrea M., Rosano, Caterina, Torres-Oviedo, Gelsy
Formato: equations & formulas pictorial research tables/charts Journal Article
Publicado: Frontiers Media S.A. 2024
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: Frontiers in Aging Neuroscience
      issn: 16634365
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      dt: 2024
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      pub: Frontiers Media S.A.
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        10.3389/fnagi.2023.1283376
        175171957
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        atl: Novel attentional gait index reveals a cognitive ability-related decline in gait automaticity during dual-task walking.
      aug:
        au:
          Shuqi Liu
          Rosso, Andrea L.
          Baillargeon, Emma M.
          Weinstein, Andrea M.
          Rosano, Caterina
          Torres-Oviedo, Gelsy
        affil: Sensorimotor Learning Laboratory, Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States
      sug:
        subj:
          Gait Physiology
          Psychomotor Performance
          Walking Physiology
          Task Performance and Analysis
          Functional Status
          Cognition Evaluation
          Prefrontal Cortex Physiology
          Attention
          Human
          Aged
          Spectroscopy, Near-Infrared Methods
          Brain Radiography
          Community Living In Old Age
          Physical Mobility
          Psychological Tests
          Walking Speed
          Experimental Studies
          Descriptive Statistics
          Data Analysis Software
          Funding Source
          Aged: 65+ years
      ab: Introduction: Gait automaticity refers to the ability to walk with minimal recruitment of attentional networks typically mediated through the prefrontal cortex (PFC). Reduced gait automaticity (i.e., greater use of attentional resources during walking) is common with aging, contributing to an increased risk of falls and reduced quality of life. A common assessment of gait automaticity involves examining PFC activation using near-infrared spectroscopy (fNIRS) during dual-task (DT) paradigms, such as walking while performing a cognitive task. However, neither PFC activity nor task performance in isolation measures automaticity accurately. For example, greater PFC activation could be interpreted as worse gait automaticity when accompanied by poorer DT performance, but when accompanied by better DT performance, it could be seen as successful compensation. Thus, there is a need to incorporate behavioral performance and PFC measurements for a more comprehensive evaluation of gait automaticity. To address this need, we propose a novel attentional gait index as an analytical approach that combines changes in PFC activity with changes in DT performance to quantify automaticity, where a reduction in automaticity will be reflected as an increased need for attentional gait control (i.e., larger index). Methods: The index was validated in 173 participants (=65 y/o) who completed DTs with two levels of difficulty while PFC activation was recorded with fNIRS. The two DTs consisted of reciting every other letter of the alphabet while walking over either an even or uneven surface. Results: As DT difficulty increases, more participants showed the anticipated increase in the attentional control of gait (i.e., less automaticity) as measured by the novel index compared to PFC activation. Furthermore, when comparing across individuals, lower cognitive function was related to higher attentional gait index, but not PFC activation or DT performance. Conclusion: The proposed index better quantified the differences in attentional control of gait between tasks and individuals by providing a unified measure that includes both brain activation and performance. This new approach opens exciting possibilities to assess participant-specific deficits and compare rehabilitation outcomes from gait automaticity interventions.
      pubtype: Academic Journal
      doctype:
        equations & formulas
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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