Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio and Their Relationship with Nutritional Status and Quality of Life of Hospitalized Women with Breast Cancer.
Blood cell biomarkers, such as the neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR), have been recently used as prognostic markers in tumors. In this study, we investigated the association between NLR and PLR with sociodemographic, clinical, anthropometric, and quality of li...
| Publicado en: | Nutrition & Cancer Vol. 76; no. 3; pp. 296 - 305 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=175195010&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 175195010 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 01635581 7MS jtl: Nutrition & Cancer issn: 01635581 maglogo: N pubinfo: dt: 2024 vid: 76 iid: 3 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 175195010 175128328 175195010 175195010 10.1080/01635581.2024.2304689 175195010 ppf: 296 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio and Their Relationship with Nutritional Status and Quality of Life of Hospitalized Women with Breast Cancer. aug: au: Silva, Roberto Júnio Gomes Grippa, Wesley Rocha Pessanha, Raphael Manhães Enriquez-Martinez, Oscar Geovanny Neto, Luiz Cláudio Barreto Silva Lopes-Júnior, Luís Carlos affil: Graduate Program in Nutrition and Health at the Federal University of Espírito Santo (UFES), Vitoria, ES, Brazil sug: subj: Breast Neoplasms Diagnosis Breast Neoplasms Prognosis Breast Neoplasms Drug Therapy Nutritional Status Quality of Life Evaluation Inpatients Women's Health Neutrophil Lymphocyte Ratio Blood Platelet Lymphocyte Ratio Blood Sociodemographic Factors Anthropometry Biological Markers Blood Neoplasm Metastasis Cross Sectional Studies Brazil Nonexperimental Studies Brazil Antineoplastic Agents Therapeutic Use Logistic Regression Marital Status Odds Ratio Confidence Intervals Ethnic Groups Race Factors Inflammation Human Male Female Middle Age Aged Data Analysis Software Descriptive Statistics Funding Source Middle Aged: 45-64 years Aged: 65+ years Male Female ab: Blood cell biomarkers, such as the neutrophil-lymphocyte ratio (NLR) and the platelet-lymphocyte ratio (PLR), have been recently used as prognostic markers in tumors. In this study, we investigated the association between NLR and PLR with sociodemographic, clinical, anthropometric, and quality of life factors of hospitalized women with non-metastatic breast cancer. A cross-sectional observational study was conducted at a reference center for oncological treatment in Southeast Brazil. Female participants aged over 18 years, with a histopathological diagnosis of stage I, II or III breast cancer, in any phase of antineoplastic treatment, were included. Our study revealed a high risk for participants, with high mean values of NLR and PLR, indicating low antitumor activity and worse prognosis. The binary logistic regression model showed that there was a significant association of the NLR marker and marital status (OR = 3.1; 95%CI = 1.06-8.57; p = 0.03) and, in relation to PLR, a trend was shown for a higher chance in women of black ethnicity to have increased PLR compared to white women (OR = 4.13; 95%CI = 0.96-17.70; p = 0.05). However, the inflammatory markers (NLR and PLR) did not show any significant association with nutritional factors. NLR and PLR are inflammatory biomarkers that can be easily obtained and measured in clinical practice. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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