Bacterial Urinary Tract Infections in North West of Iran: A Cross- Sectional Study.
Background & Objective: Bacteria play a major role in urinary tract infections (UTIs); therefore, it is necessary to be aware of their regional prevalence and the causative pathogens for better prognosis and rapid treatment in clinical settings. This study aims to evaluate the prevalence of bacteria...
| Publicado en: | Journal of Advances in Medical & Biomedical Research Vol. 31; no. 148; pp. 464 - 472 |
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| Autores principales: | , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Zanjan University of Medical Sciences & Health Services
Sep/Oct2023
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=175221108&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 175221108 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 26766264 N5MJ jtl: Journal of Advances in Medical & Biomedical Research issn: 26766264 maglogo: N pubinfo: dt: Sep/Oct2023 vid: 31 iid: 148 pid: 65276 pub: Zanjan University of Medical Sciences & Health Services artinfo: ui: 175221108 175221108 175221108 10.30699/jambs.31.148.464 175221108 ppf: 464 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Bacterial Urinary Tract Infections in North West of Iran: A Cross- Sectional Study. aug: au: Fakheri, Erfan Kazemi, Niloufar Moradi, Narges Mirzaei, Bahman affil: Student Research Committee, Zanjan University of Medical Sciences, Zanjan, Iran. sug: subj: Urinary Tract Infections Epidemiology Urinary Tract Infections Etiology Urinary Tract Infections Prognosis Bacterial Infections Epidemiology Drug Resistance, Microbial Iran Cross Sectional Studies Urinary Tract Infections Drug Therapy Disease Susceptibility Clinical Laboratories Standards Practice Guidelines Data Analysis Software Human Male Female Infant Child, Preschool Child Young Adult Adult Middle Age Aged Aged, 80 and Over Escherichia Coli Staphylococcal Infections Gram-Negative Bacterial Infections Nitrofurantoin Therapeutic Use Gram-Positive Bacteria Vancomycin Therapeutic Use Penicillins Therapeutic Use Trimethoprim Therapeutic Use Ampicillin Therapeutic Use Cross Infection Bacterial Infections Prevention and Control Bacterial Infections Urine Infant: 1-23 months Child, Preschool: 2-5 years Child: 6-12 years Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Aged, 80 & over Male Female ab: Background & Objective: Bacteria play a major role in urinary tract infections (UTIs); therefore, it is necessary to be aware of their regional prevalence and the causative pathogens for better prognosis and rapid treatment in clinical settings. This study aims to evaluate the prevalence of bacterial isolates involved in UTI samples and their antibiotics resistance pattern. Materials & Methods: In this cross-sectional study, bacterial infections from 4214 urine samples were analyzed from December 2016 to December 2018. After biochemical tests, disk diffusion susceptibility procedures were performed on all positive clinical cultures, according to CLSI guidelines. The obtained data were sorted and statistically analyzed by SPSS 26. Results: Out of 3582 suspected UTIs samples, 2006 (56%) were females and 1576 (44%) males in the 0-99 years old age range and mainly consisting of middle-aged and elderly patients (62.2%). Escherichia coli (53.43%) and Staphylococcus epidermidis (15.99%) were the most frequent isolates. Among gram negative bacteria, nitrofurantoin and among gram- positive, vancomycin represented the lowest resistance rates at 25.27% and 26.74% respectively. Piperacillin showed the least efficacy with a resistance rate of 76.04%, followed by cefazolin with a 74.94% resistance rate. In gram positive bacteria, vancomycin and gentamicin showed more promise with respective resistance rates of 19.34% and 27.34%. The highest resistance was associated with ampicillin (68.61%) and Trimethoprim/Sulfamethoxazole (66.06%). Conclusion: Alarming resistance rates were observed in ampicillin and piperacillin, which should be taken into account in therapy guidelines in this area. Prevalence of resistant strains can be avoided by developing appropriate healthcare policies and community awareness. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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