Explainable Artificial Intelligence for Deep-Learning Based Classification of Cystic Fibrosis Lung Changes in MRI...19th World Congress on Medical and Health Informatics, July 8-12, 2023, New South Wales, Australia

Algorithms increasing the transparence and explain ability of neural networks are gaining more popularity. Applying them to custom neural network architectures and complex medical problems remains challenging. In this work, several algorithms such as integrated gradients and grad came were used to g...

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Publicado en:Studies in Health Technology & Informatics Vol. 310; pp. 921 - 926
Autores principales: RINGWALD, Friedemann G., MARTYNOVA, Anna, MIERISCH, Julian, WIELPÜTZ, Mark, EISENMANN, Urs
Formato: diagnostic images proceedings research tables/charts Journal Article
Publicado: Sage Publications Inc. 2023
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Explainable Artificial Intelligence for Deep-Learning Based Classification of Cystic Fibrosis Lung Changes in MRI...19th World Congress on Medical and Health Informatics, July 8-12, 2023, New South Wales, Australia
      aug:
        au:
          RINGWALD, Friedemann G.
          MARTYNOVA, Anna
          MIERISCH, Julian
          WIELPÜTZ, Mark
          EISENMANN, Urs
        affil: Institute of Medical Informatics, Heidelberg University Hospital, Germany
      sug:
        subj:
          Lung Pathology
          Cystic Fibrosis Diagnosis
          Cystic Fibrosis Classification
          Magnetic Resonance Imaging Methods
          Image Processing, Computer Assisted Methods
          Artificial Intelligence Utilization
          Deep Learning
          Congresses and Conferences New South Wales
          New South Wales
          Human
          Neural Networks (Computer)
          Algorithms Evaluation
          Contrast Media Diagnostic Use
          Severity of Illness
          Predictive Value of Tests
      ab: Algorithms increasing the transparence and explain ability of neural networks are gaining more popularity. Applying them to custom neural network architectures and complex medical problems remains challenging. In this work, several algorithms such as integrated gradients and grad came were used to generate additional explainable outputs for the classification of lung perfusion changes and mucus plugging in cystic fibrosis patients on MRI. The algorithms are applied on top of an already existing deep learning-based classification pipeline. From six explain ability algorithms, four were implemented successfully and one yielded satisfactory results which might provide support to the radiologist. It was evident, that the areas relevant for the classification were highlighted, thus emphasizing the applicability of deep learning for classification of lung changes in CF patients. Using explainable concepts with deep learning could improve confidence of clinicians towards deep learning and introduction of more diagnostic decision support systems.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        proceedings
        research
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      ougenre: Article
    language: English
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