Clinical characteristics of people with intellectual disability admitted to hospital with constipation: identifying possible specific high‐risk factors.

Background: People with intellectual disabilities (ID) die on an average 20 years earlier to the general population. They have higher rates of multimorbidity and polypharmacy. Around 25% of people with ID report chronic constipation. The England Learning Disabilities Mortality Review found that near...

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Publicado en:Journal of Intellectual Disability Research Vol. 68; no. 3; pp. 277 - 285
Autores principales: Laugharne, R., Wilcock, M., Rees, J., Wainwright, D., Newton, N., Sterritt, J., Badger, S., Bishop, R., Bassett, P., Shankar, R.
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Mar2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2024
      vid: 68
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1111/jir.13108
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        atl: Clinical characteristics of people with intellectual disability admitted to hospital with constipation: identifying possible specific high‐risk factors.
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        au:
          Laugharne, R.
          Wilcock, M.
          Rees, J.
          Wainwright, D.
          Newton, N.
          Sterritt, J.
          Badger, S.
          Bishop, R.
          Bassett, P.
          Shankar, R.
        affil: Cornwall Intellectual Disability Equitable Research (CIDER), Cornwall Partnership NHS Foundation Trust, Truro, UK
      sug:
        subj:
          Intellectual Disability
          Patient Attitudes
          Patient Admission
          Constipation Therapy
          Constipation Risk Factors
          Risk Assessment
          Human
          Male
          Female
          Hospitals, Public
          Prospective Studies
          Data Collection Methods
          Comorbidity
          Scales
          Adult
          Middle Age
          Descriptive Statistics
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
          Female
      ab: Background: People with intellectual disabilities (ID) die on an average 20 years earlier to the general population. They have higher rates of multimorbidity and polypharmacy. Around 25% of people with ID report chronic constipation. The England Learning Disabilities Mortality Review found that nearly 25% of deaths identified constipation as a long‐term health problem. However, the likely risk factors for constipation related harm are poorly enumerated. We sought to identify possible specific high‐risk factors by examining the clinical characteristics of people with ID admitted to hospital with constipation. Methods: Data of people with ID admitted with constipation in two general hospitals covering a population of 1.3 million from 2017 to 2022 were reported using the STROBE guideline for cohort studies. Collected data included age, gender, intellectual disability severity, recorded medication, presenting complaint and co‐morbidities. The medication anticholinergic burden was calculated using the anticholinergic burden scale. Continuous variables were summarised by mean and standard deviation if normally distributed, with categorical variables summarised by the number and percentage in each category. Results: Of 46 admissions (males 52%), 57% had moderate to profound ID, 37% had epilepsy, 41% prescribed antiseizure medication (ASM) and 45% were on laxatives. Average age was 46 years. The anticholinergic burden score mean was 2.3 and median, one. Conclusions: We can hypothesise that people with more severe ID, suffering from epilepsy and on ASM may be more at risk of developing severe constipation. Some admissions may be avoided with earlier use of laxatives in the community.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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