Pharmacokinetics of oral spironolactone in infants up to 2 years of age.

Purpose: Spironolactone is a potassium sparing diuretic used for decades. Until now, pharmacokinetic (PK) studies of spironolactone have not been conducted in infants and therefore pediatric dosing is based on expert opinion. We aimed to describe the PK profiles of spironolactone and its main metabo...

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Publicado en:European Journal of Clinical Pharmacology Vol. 80; no. 2; pp. 239 - 249
Autores principales: Lass, Jana, Leroux, Stephanie, Kõrgvee, Lenne-Triin, Varendi, Heili, Kipper, Karin, Takkis, Kalev, Aro, Rudolf, Metsvaht, Tuuli, Oselin, Kersti, Pfister, Marc, Soeorg, Hiie, van den Anker, Johannes, Lutsar, Irja
Formato: research tables/charts Journal Article
Publicado: Springer Nature Feb2024
Acceso en línea:Ver este registro en EBSCOhost