A clearer vision: insights into juvenile idiopathic arthritis–associated uveitis.
The aim of this narrative review is to synthesize existing evidence-based knowledge on juvenile idiopathic arthritis–associated uveitis (JIA-U). We highlight epidemiology, pathophysiology, causes and genetics, risk factors, clinical features, diagnosis and screening, laboratory biomarkers, treatment...
| Publicado en: | Baylor University Medical Center Proceedings Vol. 37; no. 2; pp. 303 - 312 |
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| Autores principales: | , , , , , , , |
| Formato: | critical path pictorial review tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Mar2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=175362181&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 175362181 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08998280 1XEP jtl: Baylor University Medical Center Proceedings issn: 08998280 maglogo: N pubinfo: dt: Mar2024 vid: 37 iid: 2 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 175362181 175065836 175362181 175362181 10.1080/08998280.2024.2305567 175362181 ppf: 303 ppct: 9 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: A clearer vision: insights into juvenile idiopathic arthritis–associated uveitis. aug: au: M. Bani Khalaf, Ihda Jain, Hritvik Vora, Nilofar M. ul Ain, Noor Murtaza, Farhan Ram, Muskaan Doulat Nankani, Avinash Motwani, Jatin affil: Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan sug: subj: Arthritis, Juvenile Rheumatoid Uveitis Risk Factors Diagnosis, Laboratory Arthritis, Juvenile Rheumatoid Epidemiology Arthritis, Juvenile Rheumatoid Physiopathology Arthritis, Juvenile Rheumatoid Etiology Arthritis, Juvenile Rheumatoid Classification Arthritis, Juvenile Rheumatoid Diagnosis Arthritis, Juvenile Rheumatoid Symptoms Arthritis, Juvenile Rheumatoid Drug Therapy Arthritis, Juvenile Rheumatoid Prevention and Control Arthritis, Juvenile Rheumatoid Prognosis Arthritis, Juvenile Rheumatoid Complications Disease Attributes Genetics Genes Interferons Blood Sedimentation Serum Albumin Visual Acuity Retinal Detachment Risk Factors Steroids Therapeutic Use Antirheumatic Agents Therapeutic Use Early Diagnosis ab: The aim of this narrative review is to synthesize existing evidence-based knowledge on juvenile idiopathic arthritis–associated uveitis (JIA-U). We highlight epidemiology, pathophysiology, causes and genetics, risk factors, clinical features, diagnosis and screening, laboratory biomarkers, treatment options, trials with recent advances, and research challenges pertaining to JIA-U. The prevalence of JIA-U varies with different JIA subtypes, most frequently associated with the oligoarticular subtype. The risk factors involved in the development of JIA-U include younger age, antinuclear antibody (ANA) positivity, and the oligoarticular subtype of JIA, along with some specific major histocompatibility complex genes. Certain laboratory biomarkers, such as ANA, rheumatoid factor, interferon-λ, erythrocyte sedimentation rate, and transthyretin, have been used in JIA-U diagnosis, progress monitoring, and prognostication. Clinical features of JIA-U can range from asymptomatic to ophthalmic symptoms like redness, blurred vision, decreased visual acuity, hypopyon, and posterior uveitis, which can lead to retinal detachment and macular edema. The management protocol involves topical and systemic steroids, cycloplegics, disease-modifying antirheumatic drugs, biologic drugs, and surgical options. Early detection combined with prompt treatment is crucial to preventing irreversible vision loss in JIA-U. pubtype: Academic Journal doctype: critical path pictorial review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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