Rejection of Fecal Immunochemical Tests Within the Lower Gastrointestinal Diagnostic Pathway: A Cohort Study.
Introduction/Objectives: The fecal immunochemical test (FIT) helps triage primary care patients at risk of colorectal cancer (CRC). Improving FIT returns has received recent attention, however uncertainty exists regarding the accurate completion of samples provided for laboratory analysis. This stud...
| Publicado en: | Journal of Primary Care & Community Health pp. 1 - 7 |
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| Autores principales: | , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Sage Publications Inc.
2/13/2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=175442800&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 175442800 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 21501319 AZBE jtl: Journal of Primary Care & Community Health issn: 21501319 maglogo: Y pubinfo: dt: 2/13/2024 pid: 344 pub: Sage Publications Inc. place: Thousand Oaks, California artinfo: ui: 175442800 175442800 175442800 10.1177/21501319241228161 175442800 ppf: 1 ppct: 6 formats: tig: atl: Rejection of Fecal Immunochemical Tests Within the Lower Gastrointestinal Diagnostic Pathway: A Cohort Study. aug: au: Ball, Alex J. Aziz, Imran Sargur, Ravishankar B. Merriman, Louise Kurien, Matthew affil: Department of Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, South Yorkshire, UK sug: subj: Feces Analysis Immunochemistry Methods Cancer Screening Methods Colorectal Neoplasms Diagnosis Specimen Handling Diagnosis, Laboratory Rescreening Risk Factors Risk Assessment Human Early Detection of Cancer United Kingdom Electronic Health Records Record Review Data Analysis Software Descriptive Statistics Thematic Analysis Chi Square Test Pearson's Correlation Coefficient Diagnosis, Delayed Diagnostic Errors Primary Health Care Retrospective Design Sampling Error Funding Source ab: Introduction/Objectives: The fecal immunochemical test (FIT) helps triage primary care patients at risk of colorectal cancer (CRC). Improving FIT returns has received recent attention, however uncertainty exists regarding the accurate completion of samples provided for laboratory analysis. This study aims to identify the rejection rate of returned FIT samples and determine rejection causes. Methods: FIT samples from symptomatic patients within South Yorkshire, Bassetlaw, and North Derbyshire are processed at a central laboratory. Tests requests are made from 225 GP practices, which serve an estimated 2 million population. This study describes a retrospective review of FIT samples received in the central laboratory between 01/09/19 and 31/12/22. Locally held data was interrogated in March 2023 to determine the number of FIT samples received and rejected during the study period. Documented reasons for rejection were explored to identify common themes. Results: Total FIT specimens received during the study period was 126 422. Of these, 5190 (4.1%) were rejected. Monthly rejection rates fell from 17.4% in September 2019 to 1.3% in December 2022 (P <.001). Sampling errors were the most frequent cause for FIT rejection (2151/5190), with other causes including: expired specimen; no sample collection date/ time, no request form, incomplete patient information and illegible handwriting. Conclusions: This is the first study exploring FIT rejection rates in symptomatic primary care patients, which shows improvements in rejection rates over time. Targeted interventions could improve rejection rates further, thereby reducing NHS resource use and costs and diagnostic delays. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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