From book to bedside? A critical perspective on the debate about "translational bioethics".

The concept of "translational bioethics" has received considerable attention in recent years. Most publications draw an analogy to translational medicine and describe bioethical research that aims at implementing and evaluating ethical interventions. However, current accounts of translational bioeth...

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Publicado en:Bioethics Vol. 38; no. 3; pp. 177 - 187
Autores principales: Kremling, Alexander, Schildmann, Jan, Mertz, Marcel
Formato: Artículo
Publicado: Wiley-Blackwell Mar2024
Materias:
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Mar2024
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      pub: Wiley-Blackwell
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        10.1111/bioe.13240
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        atl: From book to bedside? A critical perspective on the debate about "translational bioethics".
      aug:
        au:
          Kremling, Alexander
          Schildmann, Jan
          Mertz, Marcel
        affil:
          Institute for History and Ethics of Medicine, Interdisciplinary Center for Health Sciences, Martin Luther University Halle‐Wittenberg, Halle, Germany
          Institute for Ethics, History and Philosophy of Medicine, Hannover Medical School, Hannover, Germany
      su:
        Medicine
        Health services accessibility
        Debate
        Ethical decision making
        Research ethics
        Interprofessional relations
        Bioethics
        Interdisciplinary research
        Clinical medicine research
        Translational research
      sug:
        subj:
          Medicine
          Health services accessibility
          Debate
          Ethical decision making
          Research ethics
          Interprofessional relations
          Bioethics
          Research and Development in the Physical, Engineering, and Life Sciences (except Biotechnology)
          Interdisciplinary research
          Clinical medicine research
          Translational research
      keyword:
        definition
        empirical ethics
        translational bioethics
        translational medicine
        definition
        empirical ethics
        translational bioethics
        translational medicine
      ab: The concept of "translational bioethics" has received considerable attention in recent years. Most publications draw an analogy to translational medicine and describe bioethical research that aims at implementing and evaluating ethical interventions. However, current accounts of translational bioethics are often rather vague and seem to differ with regard to conceptual and methodological assumptions. It is not clear and scarcely analyzed what exactly "translation" in the field of bioethics means, in particular regarding goals and processes so that it is justified to appeal to translational medicine. In this article, we thus explore possible analogies and disanalogies between translational medicine and translational bioethics to establish whether the often occurring reference to concepts of translational medicine in the field of bioethics can be justified by substantial analogies. We will first provide an account of different models of translational medicine. In a second step, we will propose an analytic definition that explicitly articulates the essential characteristics of "translational research" irrespective of the research field (i.e., biomedicine, bioethics). Subsequently, we will explore whether and in how far general characteristics and phases of translational research in medicine can be applied to translational research in bioethics. Based on our analyses, we will come to the skeptical conclusion that at present there are considerable conceptual disanalogies and unsolved conceptual problems that disallow using "translational bioethics" in a meaningful analogy to respective accounts in biomedicine. Nevertheless, we will demonstrate that some insights gained by the conceptual accounts of translational medicine can contribute to advance current research activities in bioethics.
      pubtype: Academic Journal
      doctype: Article
      src: R
    language: English
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