Does a multimodal prehabilitation program improve sleep quality and duration in patients undergoing colorectal resection for cancer? Pilot randomized control trial.

Sleep difficulties are a common symptom in cancer patients at different stages of treatment trajectory and may lead to numerous negative consequences for which management is required. This pilot Randomized Controlled Trial (RCT) aims to assess the potential effectiveness of home-based prehabilitatio...

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Publicado en:Journal of Behavioral Medicine Vol. 47; no. 1; pp. 43 - 62
Autores principales: Atoui, Sarah, Carli, Francesco, Bernard, Paquito, Lee, Lawrence, Stein, Barry, Charlebois, Patrick, Liberman, A. Sender
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Springer Nature Feb2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2024
      vid: 47
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10865-023-00437-3
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        atl: Does a multimodal prehabilitation program improve sleep quality and duration in patients undergoing colorectal resection for cancer? Pilot randomized control trial.
      aug:
        au:
          Atoui, Sarah
          Carli, Francesco
          Bernard, Paquito
          Lee, Lawrence
          Stein, Barry
          Charlebois, Patrick
          Liberman, A. Sender
        affil: https://ror.org/04cpxjv19 Division of Experimental Surgery, Department of Surgery, McGill University Health Centre, Montreal, QC, Canada
      sug:
        subj:
          Colorectal Neoplasms Surgery
          Home Health Care Methods
          Cancer Patients
          Prehabilitation
          Sleep Quality
          Quality of Health Care
          Human
          Canada
          Randomized Controlled Trials
          Random Assignment
          Male
          Female
          Aged
          Descriptive Statistics
          Funding Source
          Odds Ratio
          Confidence Intervals
          Combined Modality Therapy
          Sleep Duration
          Anxiety Prevention and Control
          Aged: 65+ years
          Male
          Female
      ab: Sleep difficulties are a common symptom in cancer patients at different stages of treatment trajectory and may lead to numerous negative consequences for which management is required. This pilot Randomized Controlled Trial (RCT) aims to assess the potential effectiveness of home-based prehabilitation intervention (prehab) on sleep quality and parameters compared to standard care (SOC) in colorectal cancer patients during the preoperative period and up to 8 weeks after the surgery. One hundred two participants (48.3% female, mean age 65 years) scheduled for elective resection of colorectal cancer were randomized to the prehab (n = 50) or the SOC (n = 52) groups. Recruitment and retention rates were 54% and 72%, respectively. Measures were completed at the baseline and preoperative, 4- and 8-week after-surgery follow-ups. Our mixed models' analyses revealed no significant differences between groups observed over time for all subjective and objective sleep parameters. A small positive change was observed in the perceived sleep quality only at the preoperative time point for the prehabilitation group compared to the SOC group, with an effect size d = 0.11 and a confidence interval (CI) between − 2.1 and − 0.1, p =.048. Prehab group patients with high anxiety showed a significant improvement in the rate of change of sleep duration over time compared to the SOC group, with a difference of 110 min between baseline and 8 weeks after surgery (d = 0.51, 95% CI: 92.3 to 127.7, p =.02). Multimodal prehabilitation intervention is feasible in colorectal cancer patients and may improve sleep duration for patients with high anxiety symptoms. Future large-scale RCTs are needed to confirm our results.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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