Mask Continuous Positive Airway Pressure Increases Diaphragm Thickening Fraction in Healthy Subjects.
Introduction: The most widespread treatment for obstructive sleep apnoea and obesity hypoventilation syndrome is continuous positive airway pressure (CPAP). The addition of inspiratory support is a potential alternative. This is a physiological study to determine the effect of CPAP and inspiratory s...
| Publicado en: | Respiration Vol. 103; no. 2; pp. 100 - 105 |
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| Autores principales: | , , , , , , |
| Formato: | clinical trial equations & formulas research tables/charts Journal Article |
| Publicado: |
Karger AG
2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=175604206&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 175604206 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00257931 NKR jtl: Respiration issn: 00257931 maglogo: N pubinfo: dt: 2024 vid: 103 iid: 2 pid: 2485 pub: Karger AG artinfo: ui: 175604206 174833901 175604206 175604206 10.1159/000535990 175604206 ppf: 100 ppct: 5 formats: tig: atl: Mask Continuous Positive Airway Pressure Increases Diaphragm Thickening Fraction in Healthy Subjects. aug: au: Lindner, Simon Teichert, Jan Hoermann, Clara Michels, Julia D. Herth, Felix J.F. Duerschmied, Daniel Britsch, Simone affil: Department of Cardiology, Angiology, Haemostaseology and Medical Intensive Care, Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany sug: subj: Continuous Positive Airway Pressure Methods Oxygen Masks Utilization Continuous Positive Airway Pressure Equipment and Supplies Diaphragm Physiology Pressure Support Ventilation Methods Inspiration, Respiratory Evaluation Respiration Evaluation Treatment Outcomes Human Physiological Studies Volunteer Workers Ventilators, Mechanical Descriptive Statistics Tidal Volume Comparative Studies Germany Male Female Young Adult Adult Pilot Studies Diaphragm Ultrasonography Clinical Trials Adult: 19-44 years Male Female ab: Introduction: The most widespread treatment for obstructive sleep apnoea and obesity hypoventilation syndrome is continuous positive airway pressure (CPAP). The addition of inspiratory support is a potential alternative. This is a physiological study to determine the effect of CPAP and inspiratory support pressure on respiratory effort measured by diaphragm thickening fraction (DTF) in healthy volunteers. Methods: DTF was measured in spontaneously breathing, healthy volunteers during 4 phases: (I) without connection to a ventilator, (II) on a ventilator without any applied pressures, (III) with a CPAP of 5 cmH2O, and (IV) with an additional inspiratory support pressure of 5 cmH2O. Results: Twenty-nine individuals agreed to participate. DTF was similar during the first two phases (32 ± 13% and 35 ± 22%). A considerable increase in DTF to 51 ± 21% was noted in phase III. The introduction of inspiratory support pressure during phase IV led to a reduction in DTF back to 36 ± 23% (p < 0.001). Tidal volume and minute ventilation were both slightly higher in phase IV compared to phase III. Conclusion: CPAP without inspiratory support pressure increases respiratory effort measured by DTF in healthy subjects. Further research is required to investigate this phenomenon in a clinical setting. pubtype: Academic Journal doctype: clinical trial equations & formulas research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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