Impaired Outcome Evaluation During Risky Decision-Making in Individuals with Methamphetamine Use Disorder.
Decision-making is one of the cognitive domains in which drug users are commonly impaired. To our knowledge, few studies have investigated the underlying mechanism of risk-taking behavior among individuals with methamphetamine use disorder (MUD) using a computational approach. Ninety-six right-hande...
| Publicado en: | International Journal of Mental Health & Addiction Vol. 22; no. 1; pp. 299 - 319 |
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| Autores principales: | , , , |
| Formato: | Artículo |
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Springer Nature
Feb2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ssf&AN=175634539&site=ehost-live header: @attributes: shortDbName: ssf uiTerm: 175634539 longDbName: Social Sciences Full Text (H.W. Wilson) uiTag: AN controlInfo: bkinfo: jinfo: jid: 15571874 46AW jtl: International Journal of Mental Health & Addiction issn: 15571874 maglogo: N pubinfo: dt: Feb2024 vid: 22 iid: 1 pid: 237 pub: Springer Nature artinfo: ui: 175634539 10.1007/s11469-022-00873-3 ppf: 299 ppct: 20 formats: fmt: – @attributes: type: T – @attributes: type: P size: 1.8MB tig: atl: Impaired Outcome Evaluation During Risky Decision-Making in Individuals with Methamphetamine Use Disorder. aug: au: Sui, Xiao-Yang Zhang, Mingming Yuan, Ti-Fei Rao, Li-Lin affil: https://ror.org/034t30j35 CAS Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, 100101, Beijing, China https://ror.org/05qbk4x57 Department of Psychology, University of Chinese Academy of Sciences, 100049, Beijing, China https://ror.org/04c3cgg32 Research Center of Brain and Cognitive Neuroscience, Liaoning Normal University, 116029, Dalian, China Key Laboratory of Brain and Cognitive Neuroscience, Liaoning Province, 116029, Dalian, China Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiaotong University School of Medicine, 200030, Shanghai, China https://ror.org/02afcvw97 Co-Innovation Center of Neuroregeneration, Nantong University, 226001, Nantong, China https://ror.org/03rc6as71 Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People's Hospital, Tongji University School of Medicine, Shanghai, China su: Risk-taking behavior Cognition Methamphetamine Visual analog scale Employee reviews sug: subj: Risk-taking behavior Cognition Methamphetamine Visual analog scale Employee reviews keyword: Balloon Analogue Risk Task Computational modeling Craving Hierarchical Bayesian analysis Risk taking Balloon Analogue Risk Task Computational modeling Craving Hierarchical Bayesian analysis Risk taking ab: Decision-making is one of the cognitive domains in which drug users are commonly impaired. To our knowledge, few studies have investigated the underlying mechanism of risk-taking behavior among individuals with methamphetamine use disorder (MUD) using a computational approach. Ninety-six right-handed male participants (63 individuals with MUD who were currently abstinent and 33 healthy controls) were included in Experiment 1, and 94 right-handed male participants (63 individuals with MUD who were currently abstinent and 31 healthy controls) were included in Experiment 2. To investigate whether individuals with MUD exhibit different risk-taking behavior from healthy controls and understand the possible underlying psychological processes, we used the Balloon Analogue Risk Task (BART) with and without methamphetamine-related pictures and the method of computational modeling. After individuals with MUD completed the BART, a 5-min video of methamphetamine use was displayed, and individuals with MUD then rated their subjective craving using a visual analogue scale. Individuals with MUD displayed higher risk-taking behavior than healthy controls when participants were exposed to methamphetamine-related pictures. The results of computational modeling revealed that the risk-taking propensity parameter was significantly higher in individuals with MUD than in healthy controls. The craving scores were positively correlated with the risk-taking propensity parameter and the updating coefficient when individuals with MUD were exposed to methamphetamine-related pictures. Higher risk taking in individuals with MUD could be explained by differences in the risk-taking propensity parameter, which reflects how participants evaluate the outcomes. These findings can be used to guide future work in targeting the evaluation process among people with MUD. pubtype: Academic Journal doctype: Article src: R language: English refInfo: copyright: @attributes: flag: N holdings: @attributes: islocal: N |
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