Liver Transplantation for Unresectable Colorectal Liver Metastasis: Perspective and Review of Current Literature.

The treatment of unresectable colorectal liver metastasis (CRLM) has previously been limited to palliative chemotherapy. Traditionally, the role of liver transplant has not been associated with sufficient survival to justify a patient undergoing a major operation with the associated requirement for...

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Publicado en:Current Oncology Vol. 31; no. 2; pp. 1079 - 1091
Autores principales: Robinson, Todd J., Cummins, Kaelyn, Tsung, Allan
Formato: Journal Article
Publicado: MDPI Feb2024
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Liver Transplantation for Unresectable Colorectal Liver Metastasis: Perspective and Review of Current Literature.
      aug:
        au:
          Robinson, Todd J.
          Cummins, Kaelyn
          Tsung, Allan
        affil: Department of Surgery, University of Virginia, 1215 Lee Street, Charlottesville, VA 22908, USA
      sug:
      ab: The treatment of unresectable colorectal liver metastasis (CRLM) has previously been limited to palliative chemotherapy. Traditionally, the role of liver transplant has not been associated with sufficient survival to justify a patient undergoing a major operation with the associated requirement for postoperative immunosuppression. With improvements in chemotherapy options, a certain subset of patients can experience stable disease for years, which has prompted investigation into the role of liver transplant in these patients. Several recent studies have shown promising results in well-selected patients, with posttransplant survival approaching that of liver transplant recipients for other diseases. Here, we present a review of the data and current protocols for liver transplant for unresectable CRLM.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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