Kidney function and transplants in prune belly syndrome: a scoping review.
Background: Children with prune belly syndrome (PBS) are at higher risk of developing kidney dysfunction and requiring kidney replacement therapy (KRT). While studies have described surgical and survival outcomes in these populations, there has yet to be a focused synthesis of evidence regarding kid...
| Publicado en: | Pediatric Nephrology Vol. 39; no. 4; pp. 1053 - 1064 |
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| Autores principales: | , , , , , , , , , , |
| Formato: | research systematic review tables/charts Journal Article |
| Publicado: |
Springer Nature
Apr2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=175695446&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 175695446 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0931041X EF1 jtl: Pediatric Nephrology issn: 0931041X maglogo: N pubinfo: dt: Apr2024 vid: 39 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 175695446 173623844 175695446 175695446 10.1007/s00467-023-06209-0 175695446 ppf: 1053 ppct: 11 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Kidney function and transplants in prune belly syndrome: a scoping review. aug: au: Khondker, Adree Ahmad, Ihtisham Kim, Kellie Malik, Shamir Kim, Jin K. Chua, Michael Richter, Juliane Chan, Justin YH Baker, Linda A. Lorenzo, Armando J. Rickard, Mandy affil: https://ror.org/03dbr7087 Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada sug: subj: Kidney Physiopathology Kidney Transplantation Prune Belly Syndrome Renal Insufficiency, Chronic Human Scoping Review Embase Medline Kidney Failure, Chronic Outcomes (Health Care) Graft Survival Child Child, Preschool Adolescence Young Adult Child: 6-12 years Child, Preschool: 2-5 years Adolescent: 13-18 years ab: Background: Children with prune belly syndrome (PBS) are at higher risk of developing kidney dysfunction and requiring kidney replacement therapy (KRT). While studies have described surgical and survival outcomes in these populations, there has yet to be a focused synthesis of evidence regarding kidney outcomes in this population. Here, the focus of this scoping review was to highlight knowledge gaps and report standards on kidney outcomes in PBS of all ages. Methods: Following scoping review methodology, EMBASE, MEDLINE, and Scopus were searched for peer-reviewed literature that describe kidney outcomes in PBS. All studies with a broad set of kidney outcomes (such as kidney function measures, chronic kidney disease (CKD), KRT and associated outcomes) were included. Findings were summarized and qualitatively synthesized. Results: Of the 436 unique records identified, 25 were included for synthesis. A total of 17 studies (441 patients) reported on kidney insufficiency outcomes, with an estimated prevalence of CKD ranging from 8 to 66%. A total of 15 studies (314 patients) described KRT, primary kidney transplant, and outcomes. Of these, the age for KRT ranged from 4 to 21 years, and graft survival ranged from 22 to 87% by last follow-up (range 1.3–27 years). Conclusions: There is significant variability in studies reporting kidney outcomes in PBS which limits meaningful synthesis. There is a need for future studies with comprehensive reporting of confounders and drivers for kidney insufficiency in PBS. pubtype: Academic Journal doctype: research systematic review tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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