Home Oxygen After Hospitalization for COVID-19: Results From the Multi-Center OXFORD Study.
BACKGROUND: In the first months of the pandemic, prior to the introduction of proven-effective treatments, 15-37% of patients hospitalized with COVID-19 were discharged on home oxygen. After proven-effective treatments for acute COVID-19 were established by evidence-based guidelines, little remains...
| Publicado en: | Respiratory Care Vol. 69; no. 3; pp. 281 - 290 |
|---|---|
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
| Formato: | CEU research tables/charts Journal Article |
| Publicado: |
Mary Ann Liebert, Inc.
Mar2024
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=175701871&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 175701871 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00201324 4GG jtl: Respiratory Care issn: 00201324 maglogo: N pubinfo: dt: Mar2024 vid: 69 iid: 3 pid: 1365 pub: Mary Ann Liebert, Inc. place: New Rochelle, New York artinfo: ui: 175701871 175701871 175701871 10.4187/respcare.11436 175701871 ppf: 281 ppct: 9 formats: fmt: @attributes: type: P tig: atl: Home Oxygen After Hospitalization for COVID-19: Results From the Multi-Center OXFORD Study. aug: au: Freedman, Michael B. Kim, Yoo Jin Kaur, Ramandeep Jain, Bijal V. Adegunsoye, Ayodeji O. Chung, Yu-Che DeLisa, Julie A. Gardner, Jessica M. Gordon, Howard S. Greenberg, Jared A. Kaul, Malvika Khouzam, Nader Labedz, Stephanie L. Mokhlesi, Babak Rintz, Jacob Rubinstein, Israel Taylor, Analisa Vines, David L. Ziauddin, Lubna Gerald, Lynn B. sug: subj: COVID-19 Therapy Patient Discharge Home Oxygen Therapy Health Services Needs and Demand Human Education, Continuing (Credit) Male Female Adult Middle Age Aged Multicenter Studies Funding Source Retrospective Design Prospective Studies Academic Medical Centers Record Review Scales Severity of Illness Adrenal Cortex Hormones Therapeutic Use Antiviral Agents Therapeutic Use Tocilizumab Therapeutic Use Odds Ratio Confidence Intervals Age Factors Body Mass Index Diabetes Mellitus Comorbidity Hypertension Pulse Oximetry Prescriptions, Non-Drug Medical Practice, Evidence-Based Acute Disease Illinois Hospitals Random Sample Multiple Logistic Regression Correlational Studies Data Analysis Software Descriptive Statistics Interrater Reliability Risk Assessment Hospitalization Adult: 19-44 years Middle Aged: 45-64 years Aged: 65+ years Male Female ab: BACKGROUND: In the first months of the pandemic, prior to the introduction of proven-effective treatments, 15-37% of patients hospitalized with COVID-19 were discharged on home oxygen. After proven-effective treatments for acute COVID-19 were established by evidence-based guidelines, little remains known about home oxygen requirements following hospitalization for COVID-19. METHODS: This was a retrospective, multi-center cohort study of subjects hospitalized for COVID-19 between October 2020-September 2021 at 3 academic health centers. Information was abstracted from electronic health records at the index hospitalization and for 60 d after discharge. The World Health Organization COVID-19 Clinical Progression Scale score was used to identify patients with severe COVID-19. RESULTS: Of 517 subjects (mean age 58 y, 47% female, 42% Black, 36% Hispanic, 22% with severe COVID-19), 81% were treated with systemic corticosteroids, 61% with remdesivir, and 2.5% with tocilizumab. About one quarter of subjects were discharged on home oxygen (26% [95% CI 22-29]). Older age (adjusted odds ratio [aOR] 1.02 per 5 y [95% CI 1.02-1.02]), higher body mass index (aOR 1.02 per kg/m2 [1.00-1.04]), diabetes (yes vs no, aOR 1.73 [1.46-2.02]), severe COVID-19 (vs moderate, aOR 3.19 [2.19-4.64]), and treatment with systemic corticosteroids (yes vs no, aOR 30.63 [4.51-208.17]) were associated with an increased odds of discharge on home oxygen. Comorbid hypertension (yes vs no, aOR 0.71 [0.66-0.77) was associated with a decreased odds of home oxygen. Within 60 d of hospital discharge, 50% had documentation of pulse oximetry; in this group, home oxygen was discontinued in 46%. CONCLUSIONS: About one in 41 subjects were prescribed home oxygen after hospitalization for COVID-19, even after guidelines established proven-effective treatments for acute illness. Evidence-based strategies to reduce the requirement for home oxygen in patients hospitalized for COVID-19 are needed. pubtype: Academic Journal doctype: CEU research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|