Deep Learning Combined with Radiologist's Intervention Achieves Accurate Segmentation of Hepatocellular Carcinoma in Dual-Phase Magnetic Resonance Images.

Purpose. Segmentation of hepatocellular carcinoma (HCC) is crucial; however, manual segmentation is subjective and time-consuming. Accurate and automatic lesion contouring for HCC is desirable in clinical practice. In response to this need, our study introduced a segmentation approach for HCC combin...

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Publicado en:BioMed Research International Vol. 2024; pp. 1 - 14
Autores principales: Ye, Yufeng, Zhang, Naiwen, Wu, Dasheng, Huang, Bingsheng, Cai, Xun, Ruan, Xiaolei, Chen, Liangliang, Huang, Kun, Li, Zi-Ping, Wu, Po-Man, Jiang, Jinzhao, Dan, Guo, Peng, Zhenpeng
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Wiley-Blackwell 3/1/2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 3/1/2024
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        10.1155/2024/9267554
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        atl: Deep Learning Combined with Radiologist's Intervention Achieves Accurate Segmentation of Hepatocellular Carcinoma in Dual-Phase Magnetic Resonance Images.
      aug:
        au:
          Ye, Yufeng
          Zhang, Naiwen
          Wu, Dasheng
          Huang, Bingsheng
          Cai, Xun
          Ruan, Xiaolei
          Chen, Liangliang
          Huang, Kun
          Li, Zi-Ping
          Wu, Po-Man
          Jiang, Jinzhao
          Dan, Guo
          Peng, Zhenpeng
        affil: The First Clinical College of Jinan University, Guangzhou, China
      sug:
        subj:
          Deep Learning
          Radiologists
          Carcinoma, Hepatocellular Radiography
          Magnetic Resonance Imaging
          Human
          Neural Networks (Computer)
          Automation Methods
          Image Processing, Computer Assisted
          Information Retrieval
          Machine Learning
      ab: Purpose. Segmentation of hepatocellular carcinoma (HCC) is crucial; however, manual segmentation is subjective and time-consuming. Accurate and automatic lesion contouring for HCC is desirable in clinical practice. In response to this need, our study introduced a segmentation approach for HCC combining deep convolutional neural networks (DCNNs) and radiologist intervention in magnetic resonance imaging (MRI). We sought to design a segmentation method with a deep learning method that automatically segments using manual location information for moderately experienced radiologists. In addition, we verified the viability of this method to assist radiologists in accurate and fast lesion segmentation. Method. In our study, we developed a semiautomatic approach for segmenting HCC using DCNN in conjunction with radiologist intervention in dual-phase gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid- (Gd-EOB-DTPA-) enhanced MRI. We developed a DCNN and deep fusion network (DFN) trained on full-size images, namely, DCNN-F and DFN-F. Furthermore, DFN was applied to the image blocks containing tumor lesions that were roughly contoured by a radiologist with 10 years of experience in abdominal MRI, and this method was named DFN-R. Another radiologist with five years of experience (moderate experience) performed tumor lesion contouring for comparison with our proposed methods. The ground truth image was contoured by an experienced radiologist and reviewed by an independent experienced radiologist. Results. The mean DSC of DCNN-F, DFN-F, and DFN-R was 0.69 ± 0.20 (median, 0.72), 0.74 ± 0.21 (median, 0.77), and 0.83 ± 0.13 (median, 0.88), respectively. The mean DSC of the segmentation by the radiologist with moderate experience was 0.79 ± 0.11 (median, 0.83), which was lower than the performance of DFN-R. Conclusions. Deep learning using dual-phase MRI shows great potential for HCC lesion segmentation. The radiologist-aided semiautomated method (DFN-R) achieved improved performance compared to manual contouring by the radiologist with moderate experience, although the difference was not statistically significant.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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