Lack of change in blood pressure and arterial stiffness after high dairy intake in hyperinsulinemic subjects: a cross-over randomized controlled trial.

To evaluate the effects of high dairy (HD) (≥4 servings/day), compared to adequate dairy (AD) (2–3 servings/day as per Canada's Food Guide for Healthy Eating (2007)), on blood pressure (BP) and measures of arterial stiffness in hyperinsulinemic subjects. In this cross-over clinical trial, hyperinsul...

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Publicado en:Applied Physiology, Nutrition & Metabolism Vol. 49; no. 3; pp. 350 - 360
Autores principales: Arghavani, Hana, O'Connor, Sarah, Fortier, Catherine, Rudkowska, Iwona
Formato: research tables/charts randomized controlled trial Journal Article
Publicado: Canadian Science Publishing 2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 2024
      vid: 49
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      pub: Canadian Science Publishing
      place: Ottawa, Ontario
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        10.1139/apnm-2023-0053
        175822991
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        atl: Lack of change in blood pressure and arterial stiffness after high dairy intake in hyperinsulinemic subjects: a cross-over randomized controlled trial.
      aug:
        au:
          Arghavani, Hana
          O'Connor, Sarah
          Fortier, Catherine
          Rudkowska, Iwona
        affil: Endocrinology and Nephrology Axis, CHU de Québec Research Center-Université Laval, Québec, QC, Canada
      sug:
        subj:
          Hyperinsulinemia Diet Therapy
          Dairy Products
          Food Intake
          Blood Pressure Evaluation
          Arterial Stiffness Evaluation
          Human
          Crossover Design
          Randomized Controlled Trials
          Funding Source
          Portion Size
          Pulse Wave Velocity Evaluation
          Nutrition Policy
          Random Assignment
          Cholesterol Analysis
          Anthropometry Evaluation
          Lipids Analysis
          Blood Glucose Analysis
          Lipoproteins, LDL Cholesterol Analysis
          Fatty Acids, Saturated
          Adipose Tissue Analysis
          Fasting
          Insulins Analysis
          Triglycerides Analysis
      ab: To evaluate the effects of high dairy (HD) (≥4 servings/day), compared to adequate dairy (AD) (2–3 servings/day as per Canada's Food Guide for Healthy Eating (2007)), on blood pressure (BP) and measures of arterial stiffness in hyperinsulinemic subjects. In this cross-over clinical trial, hyperinsulinemic adults were randomized to AD and HD for 6 weeks. Anthropometric, glycemic, and lipid parameters were analyzed and dietary intake was evaluated; BP, carotid-femoral pulse wave velocity, augmentation index, and measures of arterial stiffness were assessed. Twenty-seven participants completed the study. Dairy intake was 2.2 ± 1.2 servings/day during AD. In addition, lower total and low-density lipoprotein (LDL) cholesterol were observed without significant change in BP or arterial stiffness between before and after AD. During HD, the subjects consumed 5.8 ± 1.9 servings/day of dairy products, providing a higher intake of protein, saturated fat, calcium, phosphorus, sodium, and potassium compared to the baseline diet. After the HD, subjects had higher body fat, fasting insulin, homeostatic model assessment for insulin resistance (HOMA-IR) index, and triglycerides without altering BP or arterial stiffness compared to before HD. Overall, adequate or high intake of total dairy did not modify BP or arterial stiffness in hyperinsulinemic adults after 6 weeks.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        randomized controlled trial
        Journal Article
      ougenre: Article
    language: English
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