Facile Conversion and Optimization of Structured Illumination Image Reconstruction Code into the GPU Environment.

Superresolution, structured illumination microscopy (SIM) is an ideal modality for imaging live cells due to its relatively high speed and low photon-induced damage to the cells. The rate-limiting step in observing a superresolution image in SIM is often the reconstruction speed of the algorithm use...

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Publicado en:International Journal of Biomedical Imaging Vol. 2024; pp. 1 - 16
Autores principales: Oh, Kwangsung, Bianco, Piero R.
Formato: computer program pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 2/28/2024
Acceso en línea:Ver este registro en EBSCOhost
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      jtl: International Journal of Biomedical Imaging
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      dt: 2/28/2024
      vid: 2024
      pid: 480
      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        175940326
        175940326
        175940326
        10.1155/2024/8862387
        175940326
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        atl: Facile Conversion and Optimization of Structured Illumination Image Reconstruction Code into the GPU Environment.
      aug:
        au:
          Oh, Kwangsung
          Bianco, Piero R.
        affil: Department of Computer Science, College of Information Science & Technology, University of Nebraska Omaha, Omaha, NE 68182, USA
      sug:
        subj:
          Image Enhancement
          Microscopy Methods
          Graphical User Interface
          Algorithms
          Human
          Graphics
          Workflow
          Cost Effectiveness Analysis
          Computer Hardware
          Funding Source
      ab: Superresolution, structured illumination microscopy (SIM) is an ideal modality for imaging live cells due to its relatively high speed and low photon-induced damage to the cells. The rate-limiting step in observing a superresolution image in SIM is often the reconstruction speed of the algorithm used to form a single image from as many as nine raw images. Reconstruction algorithms impose a significant computing burden due to an intricate workflow and a large number of often complex calculations to produce the final image. Further adding to the computing burden is that the code, even within the MATLAB environment, can be inefficiently written by microscopists who are noncomputer science researchers. In addition, they do not take into consideration the processing power of the graphics processing unit (GPU) of the computer. To address these issues, we present simple but efficient approaches to first revise MATLAB code, followed by conversion to GPU-optimized code. When combined with cost-effective, high-performance GPU-enabled computers, a 4- to 500-fold improvement in algorithm execution speed is observed as shown for the image denoising Hessian-SIM algorithm. Importantly, the improved algorithm produces images identical in quality to the original.
      pubtype: Academic Journal
      doctype:
        computer program
        pictorial
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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