Impact of COVID-19 Pandemic on Patients with Serious Mental Illness (SMI) and Nonpsychiatric Control Subjects in Clinical Trials.
Objective: This study aimed to examine the impact of the COVID-19 pandemic on patients with serious mental illness (SMI), specifically relating to psychiatric morbidity, pandemic-induced stress, and ability to cope with pandemic-related precautionary measures, restrictions, and disruptions to daily...
| Publicado en: | Innovations in Clinical Neuroscience Vol. 21; no. 1-3; pp. 13 - 19 |
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| Autores principales: | , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Matrix Medical Communications, LLC
Jan-Mar2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=175951849&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 175951849 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 21588333 DAD5 jtl: Innovations in Clinical Neuroscience issn: 21588333 maglogo: N pubinfo: dt: Jan-Mar2024 vid: 21 iid: 1-3 pid: 33670 pub: Matrix Medical Communications, LLC place: West Chester, Pennsylvania artinfo: ui: 175951849 175951849 175951849 175951849 ppf: 13 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Impact of COVID-19 Pandemic on Patients with Serious Mental Illness (SMI) and Nonpsychiatric Control Subjects in Clinical Trials. aug: au: GARCIA-RADA, MARIA FE LITMAN, ROBERT E. affil: CenExel CBH Health in Gaithersburg, Maryland sug: subj: COVID-19 Pandemic Psychosocial Factors COVID-19 Prevention and Control Stay-at-Home Orders Psychosocial Factors Mental Disorders Psychosocial Factors Research Subjects Psychosocial Factors Clinical Trials Stress, Psychological Evaluation Coping Evaluation Patient Attitudes Evaluation Life Experiences Evaluation Human Psychiatric Patients Psychosocial Factors United States Comparative Studies Univariate Statistics Unpaired T-Tests Analysis of Variance Descriptive Statistics Masks Social Distancing COVID-19 Vaccines Administration and Dosage Suicidal Ideation Health Resource Utilization Psychiatric Care Utilization Mental Disorders Symptoms ab: Objective: This study aimed to examine the impact of the COVID-19 pandemic on patients with serious mental illness (SMI), specifically relating to psychiatric morbidity, pandemic-induced stress, and ability to cope with pandemic-related precautionary measures, restrictions, and disruptions to daily life. Design: A cross-sectional survey study of 277 clinical trial patients was conducted. This sample included nonpsychiatric controls (n=139) and patients with a diagnosis of bipolar disorder, major depressive disorder (MDD), or schizophrenia (n=138) located at five clinical trial sites across the United States. A univariate analysis was performed to obtain general frequencies of the sample. Unpaired t-tests were used in comparing the groups on numerical variables, and analysis of variance (ANOVA) was performed to identify difierences when comparing three or more categories. Results: Patients with SMI were more likely to report wearing face masks, avoiding large gatherings, and endorsing the use of precautionary measures, despite receiving a COVID-19 vaccine (p<0.001). A total of 70.3 percent (n=97) of all patients with SMI reported experiencing at least one episode of symptom worsening, 48 percent reported experiencing suicidal ideation, and 66 percent reported a need for increased mental healthcare due to COVID-19-related distress. Patients with SMI reported higher levels of stress, compared to controls, with patients with MDD having the highest levels of stress (p<0.001). Conclusion: These findings demonstrate an increased vulnerability to symptom worsening in patients with SMI during a pandemic and suggest the need to account for pandemic-induced psychological stress in clinical trial design, subject selection, and symptoms ratings. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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