Background Subtraction Angiography with Deep Learning Using Multi-frame Spatiotemporal Angiographic Input.

Catheter Digital Subtraction Angiography (DSA) is markedly degraded by all voluntary, respiratory, or cardiac motion artifact that occurs during the exam acquisition. Prior efforts directed toward improving DSA images with machine learning have focused on extracting vessels from individual, isolated...

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Publicado en:Journal of Digital Imaging Vol. 37; no. 1; pp. 134 - 145
Autores principales: Cantrell, Donald R., Cho, Leon, Zhou, Chaochao, Faruqui, Syed H. A., Potts, Matthew B., Jahromi, Babak S., Abdalla, Ramez, Shaibani, Ali, Ansari, Sameer A.
Formato: diagnostic images equations & formulas tables/charts Journal Article
Publicado: Springer Nature Feb2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2024
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10278-023-00921-x
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        atl: Background Subtraction Angiography with Deep Learning Using Multi-frame Spatiotemporal Angiographic Input.
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          Cantrell, Donald R.
          Cho, Leon
          Zhou, Chaochao
          Faruqui, Syed H. A.
          Potts, Matthew B.
          Jahromi, Babak S.
          Abdalla, Ramez
          Shaibani, Ali
          Ansari, Sameer A.
        affil: Department of Radiology, Northwestern University Feinberg School of Medicine, 737 N Michigan Ave, Suite 1600, 60611, Chicago, IL, USA
      sug:
        subj:
          Angiography, Digital Subtraction Methods
          Deep Learning
          Brain Radiography
          Human
          Male
          Female
          Adult
          Middle Age
          Aged
          Algorithms
          Motion Evaluation
          Software
          Descriptive Statistics
          Learning Methods
          Machine Learning
          Funding Source
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          Middle Aged: 45-64 years
          Aged: 65+ years
          Male
          Female
      ab: Catheter Digital Subtraction Angiography (DSA) is markedly degraded by all voluntary, respiratory, or cardiac motion artifact that occurs during the exam acquisition. Prior efforts directed toward improving DSA images with machine learning have focused on extracting vessels from individual, isolated 2D angiographic frames. In this work, we introduce improved 2D + t deep learning models that leverage the rich temporal information in angiographic timeseries. A total of 516 cerebral angiograms were collected with 8784 individual series. We utilized feature-based computer vision algorithms to separate the database into "motionless" and "motion-degraded" subsets. Motion measured from the "motion degraded" category was then used to create a realistic, but synthetic, motion-augmented dataset suitable for training 2D U-Net, 3D U-Net, SegResNet, and UNETR models. Quantitative results on a hold-out test set demonstrate that the 3D U-Net outperforms competing 2D U-Net architectures, with substantially reduced motion artifacts when compared to DSA. In comparison to single-frame 2D U-Net, the 3D U-Net utilizing 16 input frames achieves a reduced RMSE (35.77 ± 15.02 vs 23.14 ± 9.56, p < 0.0001; mean ± std dev) and an improved Multi-Scale SSIM (0.86 ± 0.08 vs 0.93 ± 0.05, p < 0.0001). The 3D U-Net also performs favorably in comparison to alternative convolutional and transformer-based architectures (U-Net RMSE 23.20 ± 7.55 vs SegResNet 23.99 ± 7.81, p < 0.0001, and UNETR 25.42 ± 7.79, p < 0.0001, mean ± std dev). These results demonstrate that multi-frame temporal information can boost performance of motion-resistant Background Subtraction Deep Learning algorithms, and we have presented a neuroangiography domain-specific synthetic affine motion augmentation pipeline that can be utilized to generate suitable datasets for supervised training of 3D (2d + t) architectures.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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