The Segmentation of Multiple Types of Uterine Lesions in Magnetic Resonance Images Using a Sequential Deep Learning Method with Image-Level Annotations.

Fully supervised medical image segmentation methods use pixel-level labels to achieve good results, but obtaining such large-scale, high-quality labels is cumbersome and time consuming. This study aimed to develop a weakly supervised model that only used image-level labels to achieve automatic segme...

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Publicado en:Journal of Digital Imaging Vol. 37; no. 1; pp. 374 - 386
Autores principales: Cui, Yu-meng, Wang, Hua-li, Cao, Rui, Bai, Hong, Sun, Dan, Feng, Jiu-xiang, Lu, Xue-feng
Formato: diagnostic images equations & formulas research tables/charts Journal Article
Publicado: Springer Nature Feb2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Feb2024
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      pub: Springer Nature
      place: New York, New York
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        atl: The Segmentation of Multiple Types of Uterine Lesions in Magnetic Resonance Images Using a Sequential Deep Learning Method with Image-Level Annotations.
      aug:
        au:
          Cui, Yu-meng
          Wang, Hua-li
          Cao, Rui
          Bai, Hong
          Sun, Dan
          Feng, Jiu-xiang
          Lu, Xue-feng
        affil: Department of Gynecology, Dalian Women and Children's Medical Group, 116033, Dalian, China
      sug:
        subj:
          Uterine Neoplasms Diagnosis
          Magnetic Resonance Imaging
          Deep Learning Utilization
          Image Processing, Computer Assisted
          Neural Networks (Computer)
          Sensitivity and Specificity
          Human
          Female
          Adult
          Middle Age
          Aged
          Retrospective Design
          Endometrial Neoplasms
          Leiomyoma
          Polyps
          Hyperplasia
          Descriptive Statistics
          Comparative Studies
          Uterine Diseases
          Diagnosis, Computer Assisted
          Early Detection of Cancer
          Women's Health
          Oncologic Care
          Funding Source
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
      ab: Fully supervised medical image segmentation methods use pixel-level labels to achieve good results, but obtaining such large-scale, high-quality labels is cumbersome and time consuming. This study aimed to develop a weakly supervised model that only used image-level labels to achieve automatic segmentation of four types of uterine lesions and three types of normal tissues on magnetic resonance images. The MRI data of the patients were retrospectively collected from the database of our institution, and the T2-weighted sequence images were selected and only image-level annotations were made. The proposed two-stage model can be divided into four sequential parts: the pixel correlation module, the class re-activation map module, the inter-pixel relation network module, and the Deeplab v3 + module. The dice similarity coefficient (DSC), the Hausdorff distance (HD), and the average symmetric surface distance (ASSD) were employed to evaluate the performance of the model. The original dataset consisted of 85,730 images from 316 patients with four different types of lesions (i.e., endometrial cancer, uterine leiomyoma, endometrial polyps, and atypical hyperplasia of endometrium). A total number of 196, 57, and 63 patients were randomly selected for model training, validation, and testing. After being trained from scratch, the proposed model showed a good segmentation performance with an average DSC of 83.5%, HD of 29.3 mm, and ASSD of 8.83 mm, respectively. As far as the weakly supervised methods using only image-level labels are concerned, the performance of the proposed model is equivalent to the state-of-the-art weakly supervised methods.
      pubtype: Academic Journal
      doctype:
        diagnostic images
        equations & formulas
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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