Time-varying functional connectivity predicts fluctuations in sustained attention in a serial tapping task.

The mechanisms for how large-scale brain networks contribute to sustained attention are unknown. Attention fluctuates from moment to moment, and this continuous change is consistent with dynamic changes in functional connectivity between brain networks involved in the internal and external allocatio...

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Publicado en:Cognitive, Affective & Behavioral Neuroscience Vol. 24; no. 1; pp. 111 - 126
Autores principales: Seeburger, Dolly T., Xu, Nan, Ma, Marcus, Larson, Sam, Godwin, Christine, Keilholz, Shella D., Schumacher, Eric H.
Formato: Journal Article
Publicado: Springer Nature Feb2024
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Time-varying functional connectivity predicts fluctuations in sustained attention in a serial tapping task.
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          Seeburger, Dolly T.
          Xu, Nan
          Ma, Marcus
          Larson, Sam
          Godwin, Christine
          Keilholz, Shella D.
          Schumacher, Eric H.
        affil: https://ror.org/01zkghx44 School of Psychology, Georgia Institute of Technology, Atlanta, GA, USA
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      ab: The mechanisms for how large-scale brain networks contribute to sustained attention are unknown. Attention fluctuates from moment to moment, and this continuous change is consistent with dynamic changes in functional connectivity between brain networks involved in the internal and external allocation of attention. In this study, we investigated how brain network activity varied across different levels of attentional focus (i.e., "zones"). Participants performed a finger-tapping task, and guided by previous research, in-the-zone performance or state was identified by low reaction time variability and out-of-the-zone as the inverse. In-the-zone sessions tended to occur earlier in the session than out-of-the-zone blocks. This is unsurprising given the way attention fluctuates over time. Employing a novel method of time-varying functional connectivity, called the quasi-periodic pattern analysis (i.e., reliable, network-level low-frequency fluctuations), we found that the activity between the default mode network (DMN) and task positive network (TPN) is significantly more anti-correlated during in-the-zone states versus out-of-the-zone states. Furthermore, it is the frontoparietal control network (FPCN) switch that differentiates the two zone states. Activity in the dorsal attention network (DAN) and DMN were desynchronized across both zone states. During out-of-the-zone periods, FPCN synchronized with DMN, while during in-the-zone periods, FPCN switched to synchronized with DAN. In contrast, the ventral attention network (VAN) synchronized more closely with DMN during in-the-zone periods compared with out-of-the-zone periods. These findings demonstrate that time-varying functional connectivity of low frequency fluctuations across different brain networks varies with fluctuations in sustained attention or other processes that change over time.
      pubtype: Academic Journal
      doctype: Journal Article
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    language: English
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