Does Microwave Exposure at Different Doses in the Pre/Postnatal Period Affect Growing Rat Bone Development?

Effects of pre/postnatal 2.45 GHz continuous wave (CW), Wireless-Fidelity (Wi-Fi) Microwave (MW) irradiation on bone have yet to be well defined. The present study used biochemical and histological methods to investigate effects on bone formation and resorption in the serum and the tibia bone tissue...

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Publicado en:Physiological Research Vol. 73; no. 1; pp. 157 - 173
Autores principales: KARADAYI, Aysegul Akar, SARSMAZ, Hayrunnisa Yeşil, ÇİĞEL, Ayşe, ENGİZ, Begüm Korunur, ÜNAL, Nilüfer Akgün, ÜRKMEZ, Sebati Sinan, GÜRGEN, Seren Gülşen
Formato: Journal Article
Publicado: Institute of Physiology, Academy of Sciences of the Czech Republic Feb2024
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Does Microwave Exposure at Different Doses in the Pre/Postnatal Period Affect Growing Rat Bone Development?
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          KARADAYI, Aysegul Akar
          SARSMAZ, Hayrunnisa Yeşil
          ÇİĞEL, Ayşe
          ENGİZ, Begüm Korunur
          ÜNAL, Nilüfer Akgün
          ÜRKMEZ, Sebati Sinan
          GÜRGEN, Seren Gülşen
        affil: Department of Biophysics, Faculty of Medicine, Ondokuz Mayis University Samsun, Republic of Türkiye
      sug:
      ab: Effects of pre/postnatal 2.45 GHz continuous wave (CW), Wireless-Fidelity (Wi-Fi) Microwave (MW) irradiation on bone have yet to be well defined. The present study used biochemical and histological methods to investigate effects on bone formation and resorption in the serum and the tibia bone tissues of growing rats exposed to MW irradiation during the pre/postnatal period. Six groups were created: one control group and five experimental groups subjected to low-level different electromagnetic fields (EMF) of growing male rats born from pregnant rats. During the experiment, the bodies of all five groups were exposed to 2.45 GHz CW-MW for one hour/day. EMF exposure started after fertilization in the experimental group. When the growing male rats were 45 days old in the postnatal period, the control and five experimental groups' growing male and maternal rats were sacrificed, and their tibia tissues were removed. Maternal rats were not included in the study. No differences were observed between the control and five experimental groups in Receptor Activator Nuclear factor-kB (RANK) biochemical results. In contrast, there was a statistically significant increase in soluble Receptor Activator of Nuclear factor-kB Ligand (sRANKL) and Osteoprotegerin (OPG) for 10 V/m and 15 V/m EMF values. Histologically, changes in the same groups supported biochemical results. These results indicate that pre/postnatal exposure to 2.45 GHz EMF at 10 and 15 V/m potentially affects bone development.
      pubtype: Academic Journal
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    language: English
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