Chemical profile, in vitro pharmacological activity and Satureja cuneifolia Ten. evaluation of essential oil based on distillation time.
The medicinal plant Satureja cuneifolia Ten. was widely utilized as spice, tea and traditional medicine. The objective of the current study was to examine the chemical composition and in vitro biological activities (LOX, MMP-1, and MMP-12 enzyme inhibition activity and cytotoxicity on A549 cell line...
| Publicado en: | International Journal of Environmental Health Research Vol. 34; no. 4; pp. 1944 - 1961 |
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| Autores principales: | , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Apr2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=176211503&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 176211503 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: Apr2024 vid: 34 iid: 4 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 176211503 162527990 176211503 176211503 10.1080/09603123.2023.2190960 176211503 ppf: 1944 ppct: 17 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Chemical profile, in vitro pharmacological activity and Satureja cuneifolia Ten. evaluation of essential oil based on distillation time. aug: au: Yıldız, Gülsüm İlgün, Selen Şeker Karatoprak, Gökçe Köse, Yavuz Bülent Göger, Fatih Temel, Halide Edip Demirci, Betül affil: Faculty of Pharmacy, Department of Pharmacognosy, Van Yuzuncu Yil University, Van, Turkiye sug: subj: Plant Extracts Pharmacodynamics Essential Oils Analysis Chromatography, Liquid Plants, Medicinal Analysis Mass Spectrometry Time Factors Human In Vitro Studies Enzyme Inhibitors Comparative Studies Cell Line Gas Chromatography-Mass Spectrometry ab: The medicinal plant Satureja cuneifolia Ten. was widely utilized as spice, tea and traditional medicine. The objective of the current study was to examine the chemical composition and in vitro biological activities (LOX, MMP-1, and MMP-12 enzyme inhibition activity and cytotoxicity on A549 cell line) of Satureja cuneifolia extracts and essential oils. The essential oils of the flowering aerial parts were hydro-distilled at four different distillation times (5, 30, 60, and 180 min) using the Clevenger apparatus. The total essential oil and four fragments were compared in terms of the major component, yield, and distillation time. Volatile compounds of the infusion were extracted by using HS-SPME. Ethanolic extract had the strongest inhibition activity on the LOX enzyme (84.50%), while the essential oils exhibited more cytotoxic activity on the A549 cell line than the extracts. The oils and the infusion were analyzed using GC-MS and the primary chemicals identified by LC-MS/MS. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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