Reduction of ovarian reserves and activation of necroptosis to in vivo air pollution exposures.
We investigated the association between air pollution and changes in ovarian follicles, anti-mullerian hormone (AMH) levels, the occurrence of necroptosis cell death by activation of receptor-interacting protein kinase 3 (RIPK3) and, the activation of mixed lineage kinase domain-like (MLKL) proteins...
| Publicado en: | International Journal of Environmental Health Research Vol. 34; no. 4; pp. 2052 - 2067 |
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| Autores principales: | , , , , , , , , , |
| Formato: | equations & formulas pictorial research tables/charts Journal Article |
| Publicado: |
Taylor & Francis Ltd
Apr2024
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=176211509&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 176211509 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 09603123 57L jtl: International Journal of Environmental Health Research issn: 09603123 maglogo: Y pubinfo: dt: Apr2024 vid: 34 iid: 4 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 176211509 176211509 176211509 10.1080/09603123.2023.2210109 176211509 ppf: 2052 ppct: 15 formats: fmt: – @attributes: type: T – @attributes: type: P tig: atl: Reduction of ovarian reserves and activation of necroptosis to in vivo air pollution exposures. aug: au: Namvar, Zahra Ramezani Tehrani, Fahimeh Shahsavani, Abbas Khodagholi, Fariba Hashemi, Seyed Saeed Binayi, Fateme Salimi, Mina Abdollahifar, Mohammad-Amin Hopke, Philip K. Mohseni-Bandpei, Anoushiravan affil: Department of Environmental Health Engineering, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran sug: subj: Air Pollution Adverse Effects Ovarian Reserve Evaluation Ovary Physiopathology Necroptosis Sex Hormones Blood In Vivo Studies Rats Environmental Exposure Funding Source ab: We investigated the association between air pollution and changes in ovarian follicles, anti-mullerian hormone (AMH) levels, the occurrence of necroptosis cell death by activation of receptor-interacting protein kinase 3 (RIPK3) and, the activation of mixed lineage kinase domain-like (MLKL) proteins. Forty-two female Wistar rats were divided into three groups of 14 each, which were exposed to real-ambient air, filtered air and purified air (control) in two periods of 3 and 5 months. The results showed that the number of ovarian follicles decreased in the group exposed to real-ambient air versus the control group (P < 0.0001). The trend of age-related AMH changes with respect to exposure to air pollutants was affected and its levels decreased after 3 months of exposure. The MLKL increased in the group exposed to the real-ambient air compared to the control group (P = 0.033). Apparently long-term exposure to air pollution can reduce ovarian reserves. pubtype: Academic Journal doctype: equations & formulas pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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