Recruitment Methods, Inclusion, and Successful Participation in a Longitudinal Clinical Trial Using Ecological Momentary Assessment.

Underrepresentation of historically marginalized populations in clinical trials continues to threaten the validity of health intervention research. Evidence supports the merits of intercept and other proactive forms of recruitment for achieving more equitable representation. However, researchers als...

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Publicado en:Health Education & Behavior Vol. 51; no. 2; pp. 280 - 291
Autores principales: Porticella, Norman, Cannon, Julie S., Wu, Chung Li, Ferguson, Stuart G., Thrasher, James F., Hackworth, Emily E., Niederdeppe, Jeff
Formato: research tables/charts Journal Article
Publicado: Sage Publications Inc. Apr2024
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Recruitment Methods, Inclusion, and Successful Participation in a Longitudinal Clinical Trial Using Ecological Momentary Assessment.
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          Porticella, Norman
          Cannon, Julie S.
          Wu, Chung Li
          Ferguson, Stuart G.
          Thrasher, James F.
          Hackworth, Emily E.
          Niederdeppe, Jeff
        affil: Department of Communication, Cornell University, Ithaca, NY, USA
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        subj:
          Research Subject Recruitment Methods
          Task Performance and Analysis
          Research Subject Retention
          Randomized Controlled Trials
          Psychological Tests
          Tobacco Products
          Product Labeling Evaluation
          Consumer Health Information Evaluation
          Human
          Secondary Analysis
          Funding Source
          Internet
          Advertising
          Income
          Educational Status
          Health Literacy
          Ethnic Groups
          Sociodemographic Factors
          Health Status Disparities
          New York
          South Carolina
          Data Analysis Software
          Post Hoc Analysis
          Descriptive Statistics
          Chi Square Test
          Odds Ratio
          Confidence Intervals
          Health Promotion
      ab: Underrepresentation of historically marginalized populations in clinical trials continues to threaten the validity of health intervention research. Evidence supports the merits of intercept and other proactive forms of recruitment for achieving more equitable representation. However, researchers also report lower retention and adherence to protocols among these populations, particularly in longitudinal studies. Few studies have compared recruitment methods for longitudinal randomized trials testing health interventions, with even fewer having done so for trials involving ecological momentary assessment (EMA). As intervention research integrates EMA and other data collection approaches requiring substantial participant effort, it is critical to better understand the effectiveness and implications of strategies to improve the representativeness of health research. This secondary data analysis compared outcomes of proactive and reactive recruitment strategies (mobile lab intercepts and internet/flyer advertising, respectively) in study inclusion, task completion, and retention within a 14-day randomized controlled trial that used EMA to evaluate cigarette package health messages. Proactive recruitment resulted in higher proportions of participants with low income and education, limited health literacy, and of diverse racial/ethnic makeup. However, this recruitment method also resulted in lower task completion, especially in the second week of the trial period, and lower retention, although group differences were not explained by participant sociodemographic characteristics targeted by inclusion efforts. We conclude that proactive recruitment via intercepts is an effective strategy for health intervention research that aims to include stakeholders from historically marginalized groups but that researchers and funders must recognize these methods require additional resources, considerations, and capacity to address non-trivial challenges to successful participation.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
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      ougenre: Article
    language: English
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