Effects of amino acid supplementation on muscle mass, muscle performance and functional capacity in subjects undergoing total knee arthroplasty: a systematic review of randomized clinical trials.

The aim of the present study was to summarize the effectiveness of amino acid supplementation on muscle strength, muscle volume, and functional capacity in patients undergoing total knee arthroplasty. For this, in November 2022, a search was carried out in the PubMed, Cochrane Library, and EMBASE da...

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Publicado en:European Journal of Orthopaedic Surgery & Traumatology Vol. 34; no. 3; pp. 1717 - 1730
Autores principales: de Souza Borges, Jose Humberto, Junior, Paulo Lobo, de Brito, Felipe Fagundes, Rezende, Heitor Paes, de Souza Silva, Marcos Vinicius, Oliveira, Marcio, Barin, Fabrício Reichert
Formato: research systematic review tables/charts Journal Article
Publicado: Springer Nature Apr2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2024
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s00590-023-03824-3
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        atl: Effects of amino acid supplementation on muscle mass, muscle performance and functional capacity in subjects undergoing total knee arthroplasty: a systematic review of randomized clinical trials.
      aug:
        au:
          de Souza Borges, Jose Humberto
          Junior, Paulo Lobo
          de Brito, Felipe Fagundes
          Rezende, Heitor Paes
          de Souza Silva, Marcos Vinicius
          Oliveira, Marcio
          Barin, Fabrício Reichert
        affil: Research and Education Institute of the Orthopedics and Specialized Medicine Hospital (IPE-HOME), SGAS Quadra 613-Conjunto C, 70200-730, Brasília, Distrito Federal, Brazil
      sug:
        subj:
          Amino Acids Pharmacodynamics
          Dietary Supplementation
          Muscle, Skeletal Pathology
          Muscle Strength
          Physical Performance
          Functional Status
          Arthroplasty, Replacement, Knee
          Human
          Systematic Review
          PubMed
          Cochrane Library
          Embase
          Male
          Female
          Middle Age
          Aged
          Aged, 80 and Over
          Isokinetic Exercises
          Quadriceps Muscles
          Middle Aged: 45-64 years
          Aged: 65+ years
          Aged, 80 & over
          Male
          Female
      ab: The aim of the present study was to summarize the effectiveness of amino acid supplementation on muscle strength, muscle volume, and functional capacity in patients undergoing total knee arthroplasty. For this, in November 2022, a search was carried out in the PubMed, Cochrane Library, and EMBASE databases, identifying a total of 2182 documents, of which only 4 were included in the present review. The included studies had 148 participants (47 men and 101 women), with a minimum age of 53 and a maximum of 92 years, and supplementation times of 13 to 30 days (1 to 3 times a day). For the results, in relation to muscle performance, when comparing the control and experimental groups, greater muscle atrophy was observed in the pre- and post-moments of the control group, in relation to the experimental group. In addition, studies suggest a good tendency for muscle mass gain, and improvement in the functional capacities of patients who used supplementation. Therefore, the use of amino acids after TKA surgery reduces muscle atrophy, which preserves muscle mass and leads to better performance in tests of strength and functional capacity, when compared to the use of a placebo.
      pubtype: Academic Journal
      doctype:
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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