The impact of different states of type 2 diabetes when stratified by baseline HbA1c on the periodontal outcomes of non‐surgical periodontal treatment: A systematic review and network meta‐analysis.

Background: Type 2 diabetes mellitus (T2DM) has been considered by many studies to have a bidirectional relationship with periodontitis. This systematic review and network meta‐analysis aimed to investigate the impact of different states of T2DM when stratified by baseline HbA1c on the clinical outc...

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Publicado en:International Journal of Dental Hygiene Vol. 22; no. 2; pp. 401 - 414
Autores principales: Kang, Shuai, Liu, Zheng‐ya, Yuan, Huan‐huan, Wang, Shu‐min, Pan, Ge‐ge, Wei, Wei, Jiang, Yi, Hou, Yu
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Wiley-Blackwell May2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2024
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: The impact of different states of type 2 diabetes when stratified by baseline HbA1c on the periodontal outcomes of non‐surgical periodontal treatment: A systematic review and network meta‐analysis.
      aug:
        au:
          Kang, Shuai
          Liu, Zheng‐ya
          Yuan, Huan‐huan
          Wang, Shu‐min
          Pan, Ge‐ge
          Wei, Wei
          Jiang, Yi
          Hou, Yu
        affil: Institute of Stomatology, Chinese People's Liberation Army No.989 hospital, Luoyang, China
      sug:
        subj:
          Diabetes Mellitus, Type 2 Complications
          Chronic Periodontitis Therapy
          Dental Scaling
          Glycated Hemoglobin
          Human
          Meta Analysis
          Systematic Review
          Prospective Studies
          Qualitative Studies
          Confidence Intervals
          Descriptive Statistics
          Literature Review
          Bias (Research)
          PubMed
          Embase
          Cochrane Library
      ab: Background: Type 2 diabetes mellitus (T2DM) has been considered by many studies to have a bidirectional relationship with periodontitis. This systematic review and network meta‐analysis aimed to investigate the impact of different states of T2DM when stratified by baseline HbA1c on the clinical outcomes of non‐surgical periodontal treatment (NSPT). Methods: This study followed the Preferred Reporting Items for Meta‐Analyses (PRISMA) guidelines and involved an electronic literature search (from inception to the 2nd of January 2023). The study included at least two groups of patients: chronic periodontitis only (No‐DM) or periodontitis and well‐controlled/poorly controlled type 2 diabetes mellitus (WC/PC‐T2DM). Clinical outcomes included probing depth (PD) reduction, bleeding on probing reduction, and clinical attachment level (CAL) gain. Direct and indirect comparisons between groups were assessed by network meta‐analysis, thus allowing us to establish a treatment ranking. Results: Ten prospective cohort studies (11 data sets) were included for qualitative analysis and network meta‐analysis. The data included in this study had high consistency; in addition, a funnel plot and Egger's test showed that the articles had low publication bias. Network meta‐analysis showed that the effect of NSPT in the No‐DM group was significantly better than the WC‐T2DM group [weighted mean difference (WMD) = 0.09, 95% confidence interval (CI) (0.01, 0.18)] and the PC‐T2DM group [WMD = 0.09, 95% CI (0.01, 0.18)] in terms of CAL gain and better than the PC‐T2DM group [WMD = 0.15, 95% CI (0.02, 0.28)] in terms of PD reduction. According to the surface under the cumulative ranking value, the No‐DM group had the highest probability of achieving the best outcome following NSPT. Conclusions: Collectively, our analyses show that T2DM exerts significant effects on the outcomes of NSPT.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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