Global air pollution exposure and congenital anomalies: an updated systematic review and meta-analysis of epidemiological studies.

A systematic review and meta-analysis was conducted to evaluate recent epidemiological evidence on the association of air pollution with congenital anomalies (CAs). Of 11,014 records, 49 were finally included in this meta-analysis. Per 10 μg/m3 increase in air pollutant, PM10 exposure during the 1st...

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Publicado en:International Journal of Environmental Health Research Vol. 34; no. 5; pp. 2333 - 2353
Autores principales: Feng, Yang, Liu, Xinxin, Zhang, Xiaoan, Zhao, Xin, Chang, Hui, Ouyang, Fan, Yu, Zengli, Gao, Zhan, Zhang, Huanhuan
Formato: meta analysis research systematic review tables/charts Journal Article
Publicado: Taylor & Francis Ltd May2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: May2024
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      pub: Taylor & Francis Ltd
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        10.1080/09603123.2023.2246383
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        atl: Global air pollution exposure and congenital anomalies: an updated systematic review and meta-analysis of epidemiological studies.
      aug:
        au:
          Feng, Yang
          Liu, Xinxin
          Zhang, Xiaoan
          Zhao, Xin
          Chang, Hui
          Ouyang, Fan
          Yu, Zengli
          Gao, Zhan
          Zhang, Huanhuan
        affil: College of Public Health, Zhengzhou University, Zhengzhou, China
      sug:
        subj:
          World Health
          Air Pollution Adverse Effects
          Environmental Exposure Adverse Effects
          Maternal Exposure Adverse Effects
          Particulate Matter Adverse Effects
          Abnormalities Risk Factors
          Risk Assessment
          Human
          Systematic Review
          Meta Analysis
          PubMed
          Embase
          Cochrane Library
          Heart Defects, Congenital Risk Factors
          Ductus Arteriosus, Patent Risk Factors
          Descriptive Statistics
          Confidence Intervals
          Odds Ratio
          Funding Source
      ab: A systematic review and meta-analysis was conducted to evaluate recent epidemiological evidence on the association of air pollution with congenital anomalies (CAs). Of 11,014 records, 49 were finally included in this meta-analysis. Per 10 μg/m3 increase in air pollutant, PM10 exposure during the 1st month of pregnancy and at the first trimester (T1) was associated with increased overall CAs. Further, exposure to PM10 was associated with congenital heart disease (OR = 1.055, 95% CI: 1.035, 1.074) and patent ductus arteriosus (OR = 1.094, 95% CI: 1.020, 1.168) at T1, with chromosomal anomalies during the entire pregnancy and with nervous system anomalies when exposure occurred 3 months prior to pregnancy, during the 1st, 2nd months of pregnancy and at T1. Besides, a significant association with overall CAs was observed for a combined exposure of PM10 and SO2 during the 1st month of gestation (OR: 1.101, 95% CI: 1.023, 1.180). A combined exposure of PM10 and CO was also associated with tetralogy of Fallot during 3–8 weeks of gestation (OR: 1.016, 95% CI: 1.005, 1.027). No significant associations were observed between PM2.5, NO2, and O3 exposure and CAs.
      pubtype: Academic Journal
      doctype:
        meta analysis
        research
        systematic review
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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