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Crystalluria in older people may require more attention.

Chronic kidney disease (CKD) is a major public health problem that tends to get worse with population aging, which is inevitable, considering that the elderly generally have comorbidities that can impact kidney health. The objective of this study was to emphasize the importance of observing crystall...

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Published in:Minas Gerais Medical Journal / Revista Médica de Minas Gerais Vol. 33; pp. 1 - 8
Main Author: Tavares Gomes, Glísia Mendes
Format: review Journal Article
Published: Associacao Medica de Minas Gerais 2023
Online Access:View this record in EBSCOhost
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      jtl: Minas Gerais Medical Journal / Revista Médica de Minas Gerais
      issn: 0103880X
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      dt: 2023
      vid: 33
      pid: 38810
      pub: Associacao Medica de Minas Gerais
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        10.5935/2238-3182.2023e33204
        176602215
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        atl: Crystalluria in older people may require more attention.
      aug:
        au: Tavares Gomes, Glísia Mendes
        affil: Centro de Saúde Escola Germano Sinval Faria/ENSP-Fiocruz, Rio de Janeiro, RJ, Brasil
      sug:
        subj:
          Urolithiasis Diagnosis
          Urolithiasis Therapy
          Urolithiasis Complications
          Kidney Calculi
          Kidney Diseases
          Public Health
          Metabolic Syndrome X
          Dehydration
          Comorbidity
          Aged, 80 and Over
          Aged
          Health Screening
          Ureteral Obstruction
          Diagnosis, Laboratory
          Urolithiasis Prognosis
          Urinalysis
          Aged, 80 & over
          Aged: 65+ years
      ab:
        Chronic kidney disease (CKD) is a major public health problem that tends to get worse with population aging, which is inevitable, considering that the elderly generally have comorbidities that can impact kidney health. The objective of this study was to emphasize the importance of observing crystalluria in geriatric patients, in addition to renal lithiasis, the possible triggering factors of this condition, and its renal impact. For the narrative review, related articles were searched in databases such as PubMed, BIREME, Web of Science, and Google Scholar with the themes: "Crystalluria in elderly people"; "Drugs induced crystalluria in elderly people". It can be observed that the geriatric population often presents, concomitantly, comorbidities that may contribute to the occurrence of crystalluria, which may be a factor to be considered among the criteria related to kidney injury in this group. Since in addition to encompassing already known causes of kidney damage, the elderly may suffer the negative effect of environmental, dietary, dehydration, and medication. Such variables can culminate in the formation of urinary crystals, which, secondary to their deposition in the renal parenchyma, can cause intratubular obstructive events, direct and indirect renal lesions, and urolithiasis. It is concluded that urinary crystals may be related to more common conditions, such as renal lithiasis, and to more complex diagnostic episodes that require a more refined investigation, as in crystallopathies.
        A doença renal crônica (DRC) é um grande problema de saúde pública e isso tende a se agravar com o envelhecimento populacional que é inevitável, considerando que idosos, geralmente, apresentam comorbidades que podem impactar na saúde renal. O objetivo desse trabalho foi ressaltar a importância da observação da cristalúria em pacientes geriátricos, para além da litíase renal, os possíveis fatores desencadeadores dessa condição e seu impacto renal. Para a revisão narrativa, artigos relacionados foram pesquisados em base de dados como PubMed, BIREME, Web of Science e Google Acadêmico com os temas: "Crystalluria in elderly people"; "Drugs induced crystalluria in elderly people". Pode-se observar que, a população geriátrica, muitas vezes apresenta, concomitantemente, comorbidades que podem contribuir para a ocorrência de cristalúria, podendo esta ser um fator a ser considerado entre os critérios relacionados à lesão renal nesse grupo. Visto que, além de englobar causas já conhecidas de lesão renal, idosos podem sofrer o efeito negativo de fatores ambientais, alimentares, de desidratação e medicamentosos. Tais variáveis podem culminar na formação de cristais urinários que, secundários à deposição destes no parênquima renal, podem ocasionar eventos obstrutivos intratubulares, lesões renais diretas e indiretas e urolitíase. Conclui-se que os cristais urinários podem estar relacionados a quadros mais comuns, como litíases renais, e a episódios de diagnóstico mais complexos e que requerem uma investigação mais aprimorada como nos casos das cristalopatias.
      pubtype: Academic Journal
      doctype:
        review
        Journal Article
      ougenre: Article
    language: English
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