Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic.

Background: A population-based cervical cancer screening programme is implemented in the Czech Republic. However, participation is insufficient among women over 50 years. This study aimed to estimate the potential improvement in participation through directly mailed HPV self-sampling kits (HPVssk) c...

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Publicado en:European Journal of Public Health Vol. 34; no. 2; pp. 361 - 368
Autores principales: Ngo, Ondřej, Chloupková, Renata, Cibula, David, Sláma, Jiří, Mandelová, Lucie, Hejduk, Karel, Hajdúch, Marián, Minka, Petr, Koudeláková, Vladimíra, Jaworek, Hana, Trnková, Markéta, Vaněk, Peter, Dvořák, Vladimír, Dušek, Ladislav, Májek, Ondřej
Formato: research tables/charts Journal Article
Publicado: Oxford University Press / USA Apr2024
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Apr2024
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      pub: Oxford University Press / USA
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        atl: Direct mailing of HPV self-sampling kits to women aged 50-65 non-participating in cervical screening in the Czech Republic.
      aug:
        au:
          Ngo, Ondřej
          Chloupková, Renata
          Cibula, David
          Sláma, Jiří
          Mandelová, Lucie
          Hejduk, Karel
          Hajdúch, Marián
          Minka, Petr
          Koudeláková, Vladimíra
          Jaworek, Hana
          Trnková, Markéta
          Vaněk, Peter
          Dvořák, Vladimír
          Dušek, Ladislav
          Májek, Ondřej
        affil: Institute of Health Information and Statistics of the Czech Republic, Prague, Czech Republic
      sug:
        subj:
          Papillomavirus Infections Diagnosis
          Cervix Neoplasms Diagnosis
          Mail
          Cancer Screening Czech Republic
          Self-Testing
          Women Czech Republic
          Human
          Female
          Middle Age
          Aged
          Czech Republic
          Comparative Studies
          Confidence Intervals
          Gynecologic Examination
          Descriptive Statistics
          Cervical Smears
          Funding Source
          Middle Aged: 45-64 years
          Aged: 65+ years
          Female
      ab: Background: A population-based cervical cancer screening programme is implemented in the Czech Republic. However, participation is insufficient among women over 50 years. This study aimed to estimate the potential improvement in participation through directly mailed HPV self-sampling kits (HPVssk) compared with standard invitation letters in women aged 50-65 non-participating in screening. Methods: The study recruited 1564 eligible women (no cervical cancer screening in the last 3 years or more, no previous treatment associated with cervical lesions or cervical cancer). Eight hundred women were mailed with an HPVssk (HPVssk group), and 764 women were sent a standard invitation letter (control group) inviting them to a routine screening (Pap test). The primary outcome was a comparison of the overall participation rate between study groups using a binominal regression model. Results: The participation rate in the HPVssk group was 13.4% [95% confidence interval (CI) 11.2-15.9%; 7.4% of women returned the HPVssk and 6.0% attended gynaecological examination] and 5.0% (95% CI 3.6-6.8%) in the control group. Using the binominal regression model, the difference between the groups was estimated as 7.6% (95% CI 5.0-10.2%; P<0.001). In the HPVssk group, 22% of women who returned HPVssk had a positive result and 70% of them underwent a follow-up examination. Conclusions: Compared with traditional invitation letters, the direct mailing of the HPVssk achieved a significantly higher participation rate, along with a notable HPV positivity rate among HPVssk responders. This approach offers a potentially viable method for engaging women who have not yet attended a cervical screening programme.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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